32959-59-4Relevant articles and documents
Copper-catalyzed synthesis of 2-arylbenzoxazoles from o-aminophenol derivatives with arylmethyl chlorides
Zhang, Guodong,Wang, Peng,Yang, Fan,Wu, Yangjie
, p. 57 - 63 (2015)
A facile and efficient synthesis of 2-arylbenzoxazoles via copper-catalyzed tandem condensation/oxidative reaction of o-aminophenol derivatives with arylmethyl chlorides was developed. Note that this reaction utilized arylmethyl chlorides as a new type of simple and cheap acyl sources and KNO3 as a readily available and low-cost benign oxidant.
Dowex 50W: A green mild reusable catalyst for the synthesis of 2-aryl benzoxazole derivatives in aqueous medium
Datta, Arup
, p. 341 - 347 (2021/05/19)
In this work simple efficient, one pot and environmentally friendly method was developed for the synthesis of 2-Aryl-1H-benzoxazole derivatives at 80oC using ortho-aminophenol and various aldehydes. It has been found that Dowex 50W is an effective catalyst to prepare moderate to high yield of a variety of benzoxazole derivatives through a clean and simple process. Aqueous medium, green methodology, rapid reaction, reusability of heterogeneous catalyst are the great advantages of this protocol.
Fluorinated phosphoric acid as a versatile effective catalyst for synthesis of series of benzimidazoles, benzoxazoles and benzothiazoles at room temperature
Mathapati, Sushil R.,Patil, Komal N.,Mathakari, Sujit S.,Suryawanshi, Appasaheb W.,Jadhav, Arvind H.
, p. 538 - 547 (2021/01/21)
The present work describes synthesis of a series of benzimidazoles, benzoxazoles and benzothiazoles through the cyclization of 1, 2-phenylenediamine, 2-aminothiophenol, or 2-aminophenol with aryl, aliphatic and heteroaryl aldehydes. The present synthetic protocol is very much efficient in presence of 5 mol % fluorophosphoric acid as a catalyst in ethanol solvent at room temperature. Shorter reaction time, simple work-up technique, high yields and easy availability are specific compensations of the present synthetic approach.