330-54-1 Usage
Description
Diuron, with the chemical formula 330-54-1, is a phenyl urea herbicide that serves as a pre-emergent solution for weed control. It is effective in managing the growth of germinating broad-leaved grasses and weeds across various crops and non-crop lands.
Used in Agriculture:
Diuron is used as a pre-emergent herbicide for weed control in crops such as apples, cotton, grapes, pears, pineapple, and alfalfa. It helps in controlling the growth of unwanted plants, thus promoting healthier crop development.
Used in Non-Crop Lands:
Diuron is used as an herbicide for weed control on non-crop lands, preventing the growth of unwanted vegetation in areas not designated for agriculture.
Used in Soil Sterilization:
Diuron is used as a sterilant in soil, helping to eliminate unwanted plant growth and prepare the soil for future planting or other uses.
Used in Paint and Stain Industry:
Diuron is used as a mildewcide in paints and stains, preventing the growth of mildew and mold on surfaces, thus preserving the appearance and integrity of the treated materials.
Used in Fish Production:
Diuron is used as an algicide in fish production, controlling the growth of algae in fish farming environments, which helps maintain water quality and promotes healthier fish growth.
Used in Sugar Cane Cultivation:
Diuron is used as a flowering depressant in sugar cane cultivation, helping to manage the growth and flowering patterns of the sugar cane plants, which can contribute to more efficient sugar production.
Air & Water Reactions
Very slightly soluble in water.
Reactivity Profile
Diuron is incompatible with the following: Strong acids .
Health Hazard
INHALATION: May cause irritation of nose and throat. EYES: Irritation. SKIN: Moderately irritating to skin.
Health Hazard
Acute and chronic toxicity was found to be oflow order in experimental animals, administered by oral route; repeated doses producedanemia in rats; the LD50 data, however,reported in the literature significantly differ; moderately toxic by intraperitoneal route,while the inhalation risk is low because oflow vapor pressure. Susceptible to hydrolyzeto dichloroaniline in vivo, which can causemethemoglobinemia; no evidence of carcino-genicity in an 18-month study in mice at1400 ppm (Innes et al, 1969); no adverseeffect observed in rats in 2-year feeding studies at dietary concentration level of 250 ppm(ACGIH 1986); adverse reproductive effectsmay arise from chronic exposure to high con-centration level.LD50 oral (rat): 1017 mg/kg (Lewis 1995)LD50 oral (rat): 3400 mg/kg (Hodge et al1968)LD LO intraperitoneal (mouse): 500 mg/kg.
Trade name
330541?; AF 101?; AI3-61438?;
AMETRON SC?; BOUNDRY?[C]; CHEMIURON?[C];
CEKIURON?; CRISURON?; DAILON?; DIATER?;
DI-ON?; DIREX?; DITOX?; DIUMATE? Diuron;
DIUREX?,[C]; DIUROL? Diuron; DIURON 4L?;
DMU?; DREXEL DIURON 4L?; DROPP ULTRA?;
DURAN?; DYNEX?[C] FARMCO DIURON?;
FORTEX SC?; FREEFLO?; GINSTAR?; HERBURON
500 BR?; HW 920?; KARMEX?[C]; K-4?; KARMEX
DIURON HERBICIDE?; KARMEX DW?; KROVAR
IDF?[C]; MARMER?; STRIKER?; SUP'R FLO?;
TELVAR?; TIGREX?; TREVISSIMO?; UNIDRON?;
UROX D?[C]; VONDURON?
Safety Profile
oneal routes. Questionable
carcinogen with experimental tumorigenic and
teratogenic data. Mutation data reported. When
heated to decomposition it emits highly toxic fumes
of Cland NOx. See also CHLOROPHENOLS.
Environmental Fate
Biological. Degradation of radiolabeled diuron (20 ppm) was not observed after 2 weeks of culturing with Fusarium and two unidentified microorganisms. After 80 days, only 3.5% of the applied amount evolved as 14CO2 (Lopez and Kirkwood, 1974). In 8 weeks, <20% of diuron in soil (60 ppm) was detoxified (Corbin and Upchurch, 1967). 3,4-Dichloroaniline was reported as a minor degradation product of diuron in water (Drinking Water Health Advisory, 1989) and soils (Duke et al., 1991). Under aerobic conditions, mixed cultures isolated from pond water and sediment degraded diuron (10 μg/mL) to CPDU, 3,4-dichloroaniline, 3-(3,4-dichlorophenyl)-1methylurea, carbon dioxide and a monodemethylated product. The extent of biodegradation varied with time, glycerol concentration and microbial population. The degradation halflife was <70 days at 30°C (Ellis and Camper, 1982).Thom and Agg (1975) reported that diuron is amenable to biological treatment with acclimation. Soil. Several degradation pathways were reported. The major products and reaction pathways include formation of 1-methyl-3-(3,4-dichlorophenol) urIncubation of diuron in soils releases carbon dioxide (Madhun and Freed, 1987). The rate of carbon dioxide formation nearly tripled when the soil temperature was increased from 25 to 35°C. Reported half-lives in an Adkins loamy sand are 705, 414 and 225 dThe half-lives for diuron in field soils ranged from 133 to 212 days with an average half-life of 328 days (Hill et al., 1955). Hill et al. (1955) studied the degradation of diuron using a Cecil loamy sand (1 ppm) and Brookstone silty clay loam (5 ppm) in the laboratory maintained at 27°C and 60% relative humidity. In both soils, diuron was applied on four separate occasions over 22 weeks. In both instances, the investigators observed 40% of the applied amount degraded in both soils.In a field application study, diuron did not leach below 5 cm in depth despite repeated applications or water addition (Majka and Lavy, 1977). Groundwater. According to the U.S. EPA (1986) diuron has a high potential to leach to groundwater.
Purification Methods
Recrystallise it from 95% EtOH [Beck et al. J Am Chem Soc 108 4018 1986]. [Beilstein 12 IV 1263.]
Toxicity evaluation
Diuron is a selective inhibitor of the Hill reaction in plant
photosynthesis. In some mammalian carcinogenic studies,
repeated high-dose exposure to diuron appeared to work as
a tumor promoter, and diuron may elicit tumor formation
by inducing cytotoxicity with subsequent sustained cell
proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 330-54-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,3 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 330-54:
(5*3)+(4*3)+(3*0)+(2*5)+(1*4)=41
41 % 10 = 1
So 330-54-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)
