330851-38-2

Basic information

• Product Name: MES 9191
• Synonyms: MES 9191
• CAS NO: 330851-38-2
• Molecular Weight: 308.423
• Mol File: 330851-38-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: MES 9191(CAS DataBase Reference)
• NIST Chemistry Reference: MES 9191(330851-38-2)
• EPA Substance Registry System: MES 9191(330851-38-2)

Safety Data

• Hazardous Substances Data: 330851-38-2(Hazardous Substances Data)

Upstream product

• 419569-94-1 1-benzyl-5-methoxy-N,N-dimethyl-1H-indole-3-acetamide 
• 419569-93-0 methyl 1-benzyl-5-methoxy-1H-indole-3-acetate 

Downstream Products

• 487-93-4 bufotenin 
• 1019-45-0 N,N-dimethyl-5-methoxytryptamine 

Relevant articles and documents

Aromatization of 1,6,7,7a-tetrahydro-2H-indol-2-ones by a novel process. Preparation of key-intermediate methyl 1-benzyl-5-methoxy-1H-indole-3-acetate and the syntheses of serotonin, melatonin, and bufotenin

Imine 7 of 1,4-cyclohexanedione mono-ethylene ketal 6 was reacted with maleic anhydride, affording the cyclized adduct 8. Methyl esterification of 8, accompanied by transacetalization, led to the dihydrooxindole derivative 10. Aromatization of 10 was then accomplished with POCl3, leading directly to the key-intermediate title compound 11 in 74% yield from ketone 6. Serotonin, melatonin, and bufotenin were then obtained by standard reactions.