33499-33-1Relevant articles and documents
Monomeric Octahedral Ruthenium(II) Complex Enabled meta-C-H Nitration of Arenes with Removable Auxiliaries
Fan, Zhoulong,Li, Jie,Lu, Heng,Wang, Dong-Yu,Wang, Chao,Uchiyama, Masanobu,Zhang, Ao
supporting information, p. 3199 - 3202 (2017/06/23)
A removable oxime-assisted meta-C-H nitration of arenes is reported. Mechanistic investigations and DFT calculations reveal a new monomeric octahedral ruthenium(II) complex is responsible for the meta-selective nitration. Dioxygen as a cooxidant is crucial for achieving high conversion and good yields. Moreover, the utility of the present reaction protocol is further showcased by the late-stage modification of the clinical CNS drugs Diazepam and Fluvoxamine.
Oxidative conversion of aldoximes into carboxylic acid esters
Said,Skarzewski,Mlochowski
, p. 1851 - 1862 (2007/10/02)
Aromatic and aliphatic aldoximes or their O-methyl ethers can be efficiently converted into the corresponding carboxylic acid esters by treatment with an alcoholic solution of 30% hydrogen peroxide in the presence of catalytic amounts of 2-nitrobenzeneseleninic acid. Primary alcohols give excellent to good yields, secondary ones - good to moderate, but with tertiary alcohols no esterification is observed.