33744-04-6

Basic information

• Product Name: 1-chloropyrrolidin-2-one
• CAS NO: 33744-04-6
• Molecular Formula: C₄H₆ClNO
• Molecular Weight: 119.5495
• Mol File: 33744-04-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 156.3°C at 760 mmHg
• Flash Point: 48.3°C
• Density: 1.31g/cm³
• Vapor Pressure: 2.91mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 1-chloropyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloropyrrolidin-2-one(33744-04-6)
• EPA Substance Registry System: 1-chloropyrrolidin-2-one(33744-04-6)

Safety Data

• Hazardous Substances Data: 33744-04-6(Hazardous Substances Data)

Usage

Uses

Versatile intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals; chlorination agent in organic synthesis; solvent; industrial bleach

Reactivity

Highly reactive

Importance

Important building block in the synthesis of many important chemical compounds

Safety precautions

Irritant to skin, eyes, and respiratory system; should be handled with caution in industrial or laboratory settings

Upstream product

• 616-45-5 2-pyrrolidinon 
• 1588772-25-1 5-(chloromethyl)-5-methylpyrrolidin-2-one 

Downstream Products

• 616-45-5 2-pyrrolidinon 
• 89736-55-0 1-((1R,2R)-2-Chloro-cyclohexyl)-pyrrolidin-2-one 
• 89736-55-0 1-((1R,2S)-2-Chloro-cyclohexyl)-pyrrolidin-2-one 
• 89736-66-3 1-(1-Methyl-heptyl)-pyrrolidin-2-one 
• 89736-65-2 1-(1-Chloromethyl-heptyl)-pyrrolidin-2-one 
• 89736-61-8 Acetyl-(2-chloro-octyl)-carbamic acid ethyl ester 
• 89736-64-1 1-(2-Chloro-octyl)-pyrrolidin-2-one 
• 63853-74-7 5-methoxypyrrolidin-2-one 

Relevant articles and documents

Algae-fungicide and algae-sterilization method

This invention relates to an algicide of excellent water solubility, low cost and excellent handling that is characterized in containing N-chloro-2-pyrrolidinone, as well as to an algicidal/microbicidal agent characterized in containing one or more compounds selected from cyclic N-chloro compounds and N,N'-dichloro compounds represented by formula (1). (1) (In the formula, X represents a methylene group, secondary amino group, or N-chloro group, and R represents a C2-5 alkylene group, provided that when X is an N-chloro group, R is a C2-3 alkylene group.)

Antimicrobial Haloalkyl Heterocycle Compounds

This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.

N,N′-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2): An efficient reagent for N-chlorination of amino esters, amide, and peptides

A simple, efficient, and rapid protocol for N-chlorination of various protected amino esters, amides, and peptides has been described. N,N′-dichlorobis(2,4,6-trichlorophenyl)urea has been used as a chlorinating agent and transformation takes place rapidly in mild conditions with quantitative yields. Copyright