3395-83-3

Basic information

• Product Name: p-(dimethoxymethyl)toluene
• Synonyms: p-(dimethoxymethyl)toluene;p-(Dimethoxymethyl)toluol;1-(Dimethoxymethyl)-4-methylbenzene;1-Dimethoxymethyl-4-methylbenzene;p-Methylbenzaldehyde dimethyl acetal;p-Tolualdehyde dimethyl acetal;Benzene, 1-(dimethoxymethyl)-4-methyl-;Einecs 222-244-9
• CAS NO: 3395-83-3
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• EINECS: 222-244-9
• Mol File: 3395-83-3.mol
• Article Data: 68

Chemical Properties

• Boiling Point: 196.2°Cat760mmHg
• Flash Point: 58.4°C
• Appearance: /
• Density: 0.986g/cm³
• Vapor Pressure: 0.567mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: p-(dimethoxymethyl)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: p-(dimethoxymethyl)toluene(3395-83-3)
• EPA Substance Registry System: p-(dimethoxymethyl)toluene(3395-83-3)

Safety Data

• Hazardous Substances Data: 3395-83-3(Hazardous Substances Data)

Usage

General Description

p-(dimethoxymethyl)toluene is a chemical compound with the molecular formula C9H12O2. It is a derivative of toluene, with the methoxy group attached to the para position of the benzene ring and the methoxymethyl group attached to the methyl group of toluene. p-(dimethoxymethyl)toluene is often used in the production of fragrances and flavorings due to its aromatic properties. It can also be utilized as a solvent and an intermediate in the synthesis of other organic compounds. Additionally, p-(dimethoxymethyl)toluene has potential applications in the pharmaceutical and cosmetic industries. However, it is important to handle this chemical with care as it may have health and environmental hazards if not properly managed.

InChI:InChI=1/C10H14O2/c1-8-4-6-9(7-5-8)10(11-2)12-3/h4-7,10H,1-3H3

Upstream product

• 616-42-2 dimethylsulfite 
• 104-87-0 4-methyl-benzaldehyde 
• 67-56-1 methanol 
• 106-42-3 para-xylene 
• 2698-14-8 1-methyl-4-(prop-1-enyl)benzene 
• 149-73-5 trimethyl orthoformate 
• 7450-04-6 1-((trimethylsilyl)methyl)-4-methylbenzene 
• 35779-32-9 1,3,5-tris(4-methylphenyl)-2,4-diazapenta-1,4-diene 
• 124-41-4 sodium methylate 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 74-88-4 methyl iodide 
• 622-97-9 1-ethenyl-4-methylbenzene 

Downstream Products

• 87505-91-7 2-<(4-methylphenyl)methoxymethyl>-2-(trimethylsiloxy)cyclobutanone 
• 92594-54-2 (Methoxy-p-tolyl-methyl)-phosphonic acid diethyl ester 
• 176857-99-1 C₁₅H₁₄N₂O₂S 
• 176858-01-8 C₁₆H₁₆N₂O₂S 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 79744-75-5 4-methyl-1-methoxyethylbenzene 
• 24165-63-7 1-p-tolyl-3-buten-1-ol 
• 89986-85-6 1,2-dimethoxy-1,2-di(4-methylphenyl)ethane 
• 2403-59-0 p-(diethoxymethyl)toluene 
• 1025707-53-2 2-(p-tolyl)-4H-benzo[d][1,3]dioxin 
• 1240400-40-1 C₁₇H₁₈O₂ 
• 1309647-54-8 C₁₄H₁₈O₄ 
• 100518-76-1 methyl (E)-2-oxo-4-(4-methylphenyl)but-3-enoate 
• 1435943-20-6 methyl 4-(4-methylphenyl)-5-cyano-2-hydroxy-6-phenyl-3,4-dihydro-2H-pyran-2-carboxylate 

Relevant articles and documents

Electrochemical Obtention of cis- and trans-3,6-Dimethoxy-3,6-dimethyl-1,4-cyclohexadienes

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Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

Enantioselective, Catalytic Multicomponent Synthesis of Homoallylic Amines Enabled by Hydrogen-Bonding and Dispersive Interactions

We report a one-step catalytic, enantioselective method for the preparation of homoallylic N-Boc amines directly from acetals. Reactive iminium ion intermediates are generated in situ through the combination of an acetal, a chiral thiourea catalyst, trialkylsilyl triflate, and N-Boc carbamate and are subsequently trapped by a variety of allylsilane nucleophiles. No homoallylic ether byproducts are detected, consistent with allylation of the iminium intermediate being highly favored over allylation of the intermediate oxocarbenium ion. Acetals derived from aromatic aldehydes possessing a variety of functional groups and substitution patterns yield homoallylic amines with excellent levels of enantiomeric enrichment. Experimental and computational data are consistent with an anchoring hydrogen-bond interaction between the protioiminium ion and the amide of the catalyst in the enantiodetermining transition state, and with stereodifferentiation achieved through specific noncovalent interactions (NCIs) with the catalyst pyrenyl moiety. Evidence is provided that the key NCI in the major pathway is a π-stacking interaction, contrasting with the cation-πinteractions invoked in previously studied reactions promoted by the same family of aryl-pyrrolidino-H-bond-donor catalysts.