34328-61-5 Usage
Chemical Description
3-chloro-4-fluorobenzaldehyde is a starting material used in the synthesis of the 3-substituted 4-(3-chloro-4-fluorophenyl)-1H-pyrrole derivatives.
Description
3-Chloro-4-fluorobenzaldehyde is an organic compound with the chemical formula C7H4ClFO. It is characterized by its colorless to light yellow liquid appearance and is known for its reactivity in various chemical synthesis processes.
Uses
Used in Pharmaceutical Industry:
3-Chloro-4-fluorobenzaldehyde is used as a key intermediate in the synthesis of triclosan analogs bearing an isoxazole group on the ring. These analogs are of interest due to their potential applications in the development of new drugs with improved properties, such as enhanced bioavailability, stability, and targeted action against specific diseases.
Used in Chemical Synthesis:
3-Chloro-4-fluorobenzaldehyde is also used as a versatile building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for further functionalization and modification, making it a valuable asset in the development of novel molecules with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 34328-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,3,2 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 34328-61:
(7*3)+(6*4)+(5*3)+(4*2)+(3*8)+(2*6)+(1*1)=105
105 % 10 = 5
So 34328-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClFO/c8-6-3-5(4-10)1-2-7(6)9/h1-4H
34328-61-5Relevant articles and documents
Metal-free chlorodeboronation of organotrifluoroborates
Molander, Gary A.,Cavalcanti, Livia N.
experimental part, p. 7195 - 7203 (2011/10/13)
A mild and metal-free method for the chlorodeboronation of organotrifluoroborates using trichloroisocyanuric acid (TCICA) was developed. Aryl-, heteroaryl-, alkenyl-, alkynyl-, and alkyltrifluoroborates were converted into the corresponding chlorinated products in good yields. This method proved to be tolerant of a broad range of functional groups.
Process for producing fluorobenzaldehydes
-
, (2008/06/13)
A process for producing a fluorobenzaldehyde of the formula: STR1 wherein X is a chlorine atom, a bromine atom or an iodine atom, n is an integer of from 1 to 5, and m is an integer of from 1 to 5, provided n≥m, which comprises reacting a halogenated benzaldehyde of the formula: STR2 wherein X and n are as defined above, with a metal fluoride in the presence of a catalyst, wherein at least one member selected from the group consisting of quaternary phosphonium salts and quaternary ammonium salts is used as the catalyst.
Cinnamamidohydantoins
-
, (2008/06/13)
A series of cinnamamidohydantoins are useful as anthelmintic agents.