3445-11-2 Usage
Description
N-(2-Hydroxyethyl)-2-pyrrolidone, also known as N-Methyl-2-pyrrolidone (NMP), is a colorless to deep brown to yellow liquid with a low toxicity level. It is an organic compound that is widely used in various industries due to its unique chemical properties, such as its ability to dissolve a wide range of polymers and its compatibility with many organic and inorganic materials.
Uses
Used in Chemical Synthesis:
N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent in chemical synthesis for its ability to dissolve a wide range of polymers and its compatibility with various organic and inorganic materials. This makes it a versatile compound for use in the production of various chemicals and pharmaceuticals.
Used in Paint and Coating Industry:
N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent in the paint and coating industry for its ability to improve the solubility of resins and other components, leading to better film formation and enhanced performance of the final product.
Used in Electronics Industry:
In the electronics industry, N-(2-Hydroxyethyl)-2-pyrrolidone is used as a cleaning agent for its ability to dissolve a wide range of materials, making it effective in removing contaminants and residues from electronic components during the manufacturing process.
Used in Pharmaceutical Industry:
N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent in the pharmaceutical industry for its ability to dissolve various active pharmaceutical ingredients (APIs) and excipients, facilitating the formulation of drugs with improved solubility and bioavailability.
Used in Adhesive and Sealant Industry:
In the adhesive and sealant industry, N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent to improve the solubility of adhesive and sealant formulations, leading to better bonding and sealing properties.
Used in Agriculture:
N-(2-Hydroxyethyl)-2-pyrrolidone is used in the agriculture industry as a solvent for the formulation of agrochemicals, such as pesticides and herbicides, due to its ability to dissolve a wide range of active ingredients and improve their efficacy.
Used in Water Treatment:
In the water treatment industry, N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent for the formulation of water treatment chemicals, such as flocculants and coagulants, to improve their performance in water purification processes.
Used in Textile Industry:
N-(2-Hydroxyethyl)-2-pyrrolidone is used in the textile industry as a solvent for the formulation of dyestuffs and other textile chemicals, enhancing their solubility and performance in the dyeing and finishing processes.
Used in Automotive Industry:
In the automotive industry, N-(2-Hydroxyethyl)-2-pyrrolidone is used as a solvent in the formulation of various automotive chemicals, such as paints, coatings, and adhesives, due to its ability to improve their performance and durability.
Used in Construction Industry:
N-(2-Hydroxyethyl)-2-pyrrolidone is used in the construction industry as a solvent for the formulation of construction chemicals, such as concrete additives and sealants, to enhance their performance and durability in various construction applications.
Synthesis Reference(s)
Journal of the American Chemical Society, 74, p. 4959, 1952 DOI: 10.1021/ja01139a518
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 3445-11-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,4 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3445-11:
(6*3)+(5*4)+(4*4)+(3*5)+(2*1)+(1*1)=72
72 % 10 = 2
So 3445-11-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO2/c8-5-4-7-3-1-2-6(7)9/h8H,1-5H2
3445-11-2Relevant articles and documents
Development of a new production process for N-vinyl-2-pyrrolidone
Shimasaki, Yuuji,Yano, Hitoshi,Sugiura, Hideto,Kambe, Hideyuki
, p. 449 - 459 (2008)
We describe the first continuous production process for N-vinyl-2-pyrrolidone (NVP). The starting materials are γ-butyrolactone (GBL) and monoethanolamine (MEA). The process consists of two stages: the synthesis of N-(2-hydroxy-ethyl)-2-pyrrolidone (HEP) from GBL and MEA, and the vapor-phase dehydration of HEP to NVP. The key features of this technology are the dehydration catalyst and the vapor-phase reaction system. The catalyst is of very simple composition, being alkali (or alkaline earth) metal oxides-SiO 2. Though its acid and base strengths are very weak, its catalytic performance is high. We presume that the excellent catalytic performance is due to the selective adsorption of HEP to the catalyst. Moreover, an IR spectroscopic study of the HEP-adsorbed catalyst indicated that the isolated silanol of the catalyst surface plays an important role. This account describes the progress made from the laboratory study to the industrial process, along with the experimental results and discussion.
Extending the chemical product tree: A novel value chain for the production of: N -vinyl-2-pyrrolidones from biogenic acids
Haus, Moritz Otto,Louven, Yannik,Palkovits, Regina
, p. 6268 - 6276 (2019/12/03)
The sustainable production of polymers from biogenic platform chemicals shows great promise to reduce the chemical industry's dependence on fossil resources. In this context, we propose a new two-step process leading from dicarboxylic acids, such as succinic and itaconic acid, to N-vinyl-2-pyrrolidone monomers. Firstly, the biogenic acid is reacted with ethanolamine and hydrogen using small amounts of water as solvent together with solid catalysts. For effective conversion, the optimal catalyst (carbon supported ruthenium) has to hold the ability of activating H2 as well as (imide) CO bonds. The obtained products, N-(2-hydroxyethyl)-2-pyrrolidones, are subsequently converted in a continuous gas phase dehydration over simple sodium-doped silica, with excellent selectivity of above 96 mol% and water as the sole by-product. With a final product yield of ≥72 mol% over two process steps and very little waste due to the use of heterogeneous catalysis, the proposed route appears promising-commercially as well as in terms of Green Chemistry.
Method for Producing Bio-Based Homoserine Lactone and Bio-Based Organic Acid from O-Acyl Homoserine Produced by Microorganisms
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Paragraph 0232; 0233; 0234; 0235, (2014/10/16)
The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence of an acid catalyst. According to the present invention, O-acyl homoserine produced by a microorganism is used as a raw material for producing 1,4-butanediol, gamma-butyrolactone, tetrahydrofuran and the like, which are industrially highly useful. The O-acyl homoserine produced by a microorganism can substitute conventional petrochemical products, can solve environmental concerns, including the emission of pollutants and the exhaustion of natural resources, and can be continuously renewable so as not to exhaust natural resources.
