3468-99-3 Usage
Description
Diphenyl-acetic acid ethyl ester, also known as ethyl diphenylacetate, is a colorless to light yellow liquid with a fruity odor. It is insoluble in water but soluble in organic solvents. This chemical compound is commonly used in the pharmaceutical industry and organic synthesis. Its structure and reactivity make it a versatile building block in the synthesis of various organic compounds, particularly in the production of pharmaceutical intermediates. Diphenyl-acetic acid ethyl ester has been studied for its potential anti-inflammatory and analgesic properties, making it a promising candidate for the development of novel drugs.
Uses
Used in Pharmaceutical Industry:
Diphenyl-acetic acid ethyl ester is used as a building block for the synthesis of various pharmaceutical intermediates. Its structure and reactivity make it an important component in the development of new drugs.
Used in Organic Synthesis:
Diphenyl-acetic acid ethyl ester is used as a versatile chemical in organic synthesis, contributing to the production of a wide range of organic compounds.
Used in Drug Development:
Diphenyl-acetic acid ethyl ester is used as a potential candidate for the development of novel drugs due to its potential anti-inflammatory and analgesic properties. Its study and application in this area could lead to the creation of new treatments for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 3468-99-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,6 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3468-99:
(6*3)+(5*4)+(4*6)+(3*8)+(2*9)+(1*9)=113
113 % 10 = 3
So 3468-99-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O2/c1-2-18-16(17)15(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3
3468-99-3Relevant articles and documents
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Leake,Levine
, p. 1627,1628 (1959)
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Leffek,K.T.,Matinopoulos-Scordou,A.E.
, p. 1099 - 1102 (1979)
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Photoredox Catalytic Phosphite-Mediated Deoxygenation of α-Diketones Enables Wolff Rearrangement and Staudinger Synthesis of β-Lactams
Jiang, Zhiyong,Li, Haijun,Wei, Guo,Yang, Hui
supporting information, p. 19696 - 19700 (2021/08/03)
A novel visible-light-driven catalytic activation of C=O bonds by exploiting the photoredox chemistry of 1,3,2-dioxaphospholes, readily accessible from α-diketones and trialkyl phosphites, is reported. This mild and environmentally friendly strategy provides an unprecedented and efficient access to the Wolff rearrangement reaction which traditionally entails α-diazoketones as precursors. The resulting ketenes could be precisely trapped by alcohols/thiols to give α-aryl (thio)acetates and by imines to afford the valuable β-lactams in up to 99 % yields.
Diaryl acetate compound and preparation method thereof
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Paragraph 0019-0022, (2020/04/29)
The invention provides a diaryl acetate compound and a preparation method, and the preparation method comprises the following steps: (1) adding a diary 1, 2-diketone compound, an alcohol compound, trialkyl phosphite and a photocatalyst into a reaction vessel, adding a solvent, and dissolving to obtain a reaction solution; (2) irradiating an reaction liquid by using a light source and stirring until the reaction is complete; and (3) after the reaction is finished, recovering the solvent under reduced pressure and purifying by column chromatography to obtain the diaryl acetate compound. Startingfrom easily available diaryl 1, 2-diketone, the method has the advantages of mild and green reaction conditions, no need of precious transition metal catalysis, economical performance, environmentalprotection, and high practicality.
