3485-82-3 Usage
General Description
3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, sodium salt is a chemical compound commonly known as sodium theophylline. It is a salt form of theophylline, which is a xanthine derivative and a bronchodilator medication used to treat asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the smooth muscles in the airways, making it easier to breathe. It also has the ability to stimulate the central nervous system, diuretic effects, and can increase heart rate. The sodium salt form of theophylline is often used in pharmaceutical formulations to improve its solubility and absorption in the body. However, it can also have side effects such as nausea, headaches, and palpitations, and should be used with caution in patients with certain medical conditions or when taking other medications.
Check Digit Verification of cas no
The CAS Registry Mumber 3485-82-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,8 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3485-82:
(6*3)+(5*4)+(4*8)+(3*5)+(2*8)+(1*2)=103
103 % 10 = 3
So 3485-82-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N4O2.Na/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;/h3H,1-2H3,(H,8,9);/q;+1
3485-82-3Relevant articles and documents
Preparation method of theophylline sodium salt
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, (2020/09/08)
The invention relates to the technical field of pharmaceutical chemicals, and particularly discloses a preparation method of theophylline sodium salt. The preparation method of theophylline sodium salt comprises the following process steps: mixing cyanoacetic acid and acetic anhydride for reaction to obtain mixed anhydride, and performing a condensation reaction on the mixed anhydride and 1,3-dimethylurea to obtain 1,3-dimethyl cyanoacetylurea; sequentially carrying out cyclization, nitrosation, hydrogenation and acylation on the 1,3-dimethyl cyanoacetylurea to obtain 1,3-dimethyl-4-amino-5-formylamino uracil; subjecting the 1,3-dimethyl-4-amino-5-formylamino uracil to ring closing to obtain the theophylline sodium salt. According to the preparation method, the reaction conditions are mildand easy to control, the product yield is high, byproducts are few, strong ammonia gas smell is avoided, the cost is low, and generated pollution wastes are few.
