351442-36-9

Basic information

• Product Name: (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester
• Synonyms: (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester
• CAS NO: 351442-36-9
• Molecular Weight: 1044.12
• Mol File: 351442-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester(351442-36-9)
• EPA Substance Registry System: (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-pentafluorophenyloxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester(351442-36-9)

Safety Data

• Hazardous Substances Data: 351442-36-9(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 351442-34-7 (S)-3-{5'-[(S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-2-tert-butoxycarbonyl-ethyl]-2',3'-diisopropoxy-6-methoxy-biphenyl-3-yl}-2-tert-butoxycarbonylamino-propionic acid 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 351442-30-3 2-tert-butoxycarbonylamino-3-(5'-formyl-2',3'-diisopropoxy-6-methoxy-biphenyl-3-yl)-propionic acid methyl ester 
• 351442-31-4 3-(5'-bromomethyl-2',3'-diisopropoxy-6-methoxy-biphenyl-3-yl)-2-tert-butoxycarbonylamino-propionic acid methyl ester 
• 351442-43-8 2-tert-butoxycarbonylamino-3-(5'-hydroxymethyl-2',3'-diisopropoxy-6-methoxy-biphenyl-3-yl)-propionic acid methyl ester 
• 351442-33-6 (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-[5'-((S)-2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester 
• 16414-34-9 3-bromo-4,5-dihydroxybenzaldehyde 
• 351442-24-5 2-amino-3-[5'-(2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-5,6-diisopropoxy-2'-methoxy-biphenyl-3-yl]-propionic acid tert-butyl ester 
• 351442-25-6 C₁₃H₁₉BO₅ 
• 351442-28-9 2-(3-bromo-4,5-diisopropoxy-phenyl)-[1,3]dioxolane 
• 351442-26-7 3-bromo-4,5-diisopropoxy-benzaldehyde 

Downstream Products

• 351442-21-2 2-[(14-tert-butoxycarbonylamino-11-sec-butyl-3,4-dihydroxy-19-methoxy-10,13-dioxo-9,12-diaza-tricyclo[14.3.1.1^2,6]heneicosa-1⁽²⁰⁾,2,4,6⁽²¹⁾,16,18-hexaene-8-carbonyl)-amino]-3-(4-fluoro-3-nitro-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Studies on the total synthesis of RP 66453: synthesis of fully functionalized 15-membered biaryl-containing macrocycle.

[structure: see text] Palladium-catalyzed Suzuki cross-coupling, Corey's enantioselective alkylation of glycine template, and macrolactamization are key steps in an efficient synthesis of the 15-membered macrocycle 2.