355010-37-6

Basic information

• Product Name: benzyl [2-(N-chloroformyl-N-methylamino)-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate
• Synonyms: benzyl [2-(N-chloroformyl-N-methylamino)-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate
• CAS NO: 355010-37-6
• Molecular Weight: 839.646
• Mol File: 355010-37-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl [2-(N-chloroformyl-N-methylamino)-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl [2-(N-chloroformyl-N-methylamino)-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate(355010-37-6)
• EPA Substance Registry System: benzyl [2-(N-chloroformyl-N-methylamino)-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate(355010-37-6)

Safety Data

• Hazardous Substances Data: 355010-37-6(Hazardous Substances Data)

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 191352-30-4 (2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(2-(methylamino)-4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 75-44-5 phosgene 
• 355010-36-5 benzyl [2-methylamino-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranoside]uronate 
• 355010-40-1 2-methylamino-4-nitrophenyl-2,3,4-tri-O-(tert-butyldimethylsilyl)-β-D-glucopyranosiduronic acid 
• 355010-32-1 2-methylamino-4-nitrophenyl-β-D-glucopyranosiduronic acid 

Relevant articles and documents

Prodrug Mono Therapy: Synthesis and biological evaluation of an etoposide glucuronide-prodrug

A glucuronide-based prodrug of etoposide has been synthesized for a Prodrug Mono Therapy strategy. The aim is to selectively liberate the active compound by β-D-glucuronidase already present in necrotic tumours. Outside from these sites, this enzyme is kn