3555-84-8Relevant articles and documents
A new efficient method for the preparation of intermediate aromatic ketones by Friedel–Crafts acylation
Jin, Xiaojun,Wang, Ailing,Cao, Hongyu,Zhang, Shujia,Wang, Lihao,Zheng, Xueliang,Zheng, Xuefang
, p. 5521 - 5530 (2018/04/30)
Abstract: As the most important method to prepare pharmaceutical and chemical intermediate aromatic ketones, Friedel–Crafts (F–C) acylation is used to seek a novel catalytic system which is imminently consistent with the concept of green chemistry. In this study, six deep eutectic solvents (DES) were synthesized for the Friedel–Crafts acylation reaction as a catalytic solvent. Among the six DES, choline chloride-zinc chloride ([ChCl][ZnCl2]2) proved to be the most competent candidate of electron-rich arenes with acylation reagent. It got the highest yield when 1.0 equivalent of [ChCl][ZnCl2]2 used with acyl halides at 70?°C. Recycled DES was reused directly without any extra process. After five cycles, the catalytic activity did not decrease significantly (80–85%). Finally, according to experimental validation, the possible mechanism of this reaction was considered. Graphical Abstract: [Figure not available: see fulltext.].
COMPOUND AND COMPOSITION CONTAINING THE SAME, AND METHOD FOR MANUFACTURING DEVICE USING THE COMPOSITION
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Paragraph 0152-0154, (2017/09/14)
PROBLEM TO BE SOLVED: To provide a compound which efficiently absorbs extreme ultraviolet radiation (EUV) such as KrF excimer laser and ArF excimer laser or an electron beam, has low sensitivity to OoB, and has high contrast. SOLUTION: A compound is represented by formula (1) and formula (2). In formulae (1) and (2), R1a and R1a are each independently a first monovalent organic group containing a divalent hydrocarbon group selected from an alkylene group; a group bonded directly to sulfur atom (S+) is the divalent hydrocarbon group; R2 is a hydrogen atom, an alkyl group and the like; R3 to R6 are a hydrogen atom, a hydroxy group or a second monovalent organic group; X- is a monovalent anion; and R1a and R1b in Formula (1) or R1a and R1b in Formula (2) may be bonded to each other to form a ring. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
Direct C-H Cyanation of Arenes via Organic Photoredox Catalysis
McManus, Joshua B.,Nicewicz, David A.
, p. 2880 - 2883 (2017/03/11)
Methods for the direct C-H functionalization of aromatic compounds are in demand for a variety of applications, including the synthesis of agrochemicals, pharmaceuticals, and materials. Herein, we disclose the construction of aromatic nitriles via direct C-H functionalization using an acridinium photoredox catalyst and trimethylsilyl cyanide under an aerobic atmosphere. The reaction proceeds at room temperature under mild conditions and has proven to be compatible with a variety of electron-donating and -withdrawing groups, halogens, and nitrogen- and oxygen-containing heterocycles, as well as aromatic-containing pharmaceutical agents.