363-58-6 Usage
Description
Ethyl 2-chloro-4,4,4-trifluoroacetoacetate is a colorless liquid chemical compound that serves as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure, featuring a chloro and trifluoromethyl group, provides it with specific reactivity and properties that make it valuable in the chemical and pharmaceutical industries.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-chloro-4,4,4-trifluoroacetoacetate is used as a synthetic intermediate for the preparation of furoindazole derivatives, which are GPR84 antagonists. These antagonists are useful in treating various diseases by modulating the activity of GPR84, a protein receptor that plays a role in inflammation and immune response.
Used in Organic Synthesis:
In the field of organic chemistry, Ethyl 2-chloro-4,4,4-trifluoroacetoacetate is utilized as a building block for the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique functional groups allow for various chemical reactions, such as substitution, addition, and condensation, enabling the creation of diverse molecular structures with potential applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 363-58-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 363-58:
(5*3)+(4*6)+(3*3)+(2*5)+(1*8)=66
66 % 10 = 6
So 363-58-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClF3O3/c1-2-13-5(12)3(7)4(11)6(8,9)10/h3H,2H2,1H3/t3-/m1/s1
363-58-6Relevant articles and documents
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Cherbuliez,E. et al.
, p. 1423 - 1426 (1965)
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Chalcone compound and applications thereof
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Paragraph 0115; 0116; 0117, (2020/06/17)
The present invention relates to a chalcone-containing compound represented by a general formula (I), and a pharmaceutically acceptable salt, a solvate and a prodrug thereof, wherein the substituentsR1, R2, R3, R4, R5, R6, Q and n have the meanings given in the specification. The invention further relates to applications of the compound represented by the general formula (I) in preparation of anti-tumor drugs, and applications of the compound and the pharmaceutically acceptable salt, solvate and prodrug thereof in preparation of drugs for preventing and/or relieving cancers caused by tumor cells of human tissues or organs, wherein the cancers are preferably colon cancer, liver cancer, lymphoma, lung cancer, esophageal cancer, breast cancer, central nervous system tumor, melanoma, skin cancer, ovarian cancer, cervical cancer, kidney cancer, leukemia, prostate cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharyngeal cancer, gastric cancer and the like.
Pyrazinamide compound, preparation method and applications thereof, and bactericide
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Paragraph 0115-0116, (2019/11/04)
The present invention relates to the field of pesticide bactericides, and discloses a pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound hasa structure represented by a formula (I). The preparatio
