3641-51-8 Usage
Description
(R)-(+)-Methylsuccinic acid, also known as (R)-2-methylbutanedioic acid, is a chiral organic compound with a methyl group at the 2-position having R-configuration. It is a colorless liquid and is a valuable building block in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals.
Uses
Used in Pharmaceutical Industry:
(R)-(+)-Methylsuccinic acid is used as a chiral building block for the synthesis of various pharmaceuticals. Its unique R-configuration allows for the production of enantiomerically pure compounds, which are essential for the development of effective and safe drugs.
Used in Agrochemical Industry:
(R)-(+)-Methylsuccinic acid is used as a chiral intermediate in the synthesis of agrochemicals, such as insecticides and herbicides. Its R-configuration enables the production of enantiomerically pure active ingredients, which can improve the efficacy and selectivity of these products.
Used in Specialty Chemicals:
(R)-(+)-Methylsuccinic acid is used as a chiral building block in the synthesis of various specialty chemicals, such as fragrances, flavors, and dyes. Its R-configuration allows for the creation of enantiomerically pure compounds, which can enhance the performance and properties of these products.
Used in Chiral Synthesis:
(R)-(+)-Methylsuccinic acid is used as a chiral auxiliary in asymmetric synthesis, enabling the production of enantiomerically pure compounds. Its R-configuration can be used to control the stereochemistry of reactions, leading to the formation of desired enantiomers with high selectivity.
Used in Research and Development:
(R)-(+)-Methylsuccinic acid is used as a research compound in the development of new synthetic methods, catalysts, and chiral reagents. Its R-configuration provides a valuable tool for understanding the mechanisms of asymmetric reactions and the design of novel chiral molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 3641-51-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,4 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3641-51:
(6*3)+(5*6)+(4*4)+(3*1)+(2*5)+(1*1)=78
78 % 10 = 8
So 3641-51-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H8O4/c1-3(5(8)9)2-4(6)7/h3H,2H2,1H3,(H,6,7)(H,8,9)/t3-/m1/s1
3641-51-8Relevant articles and documents
Miniolins A-C, novel isomeric furanones induced by epigenetic manipulation of Penicillium minioluteum
Tang, Hao-Yu,Zhang, Qiang,Gao, Yu-Qi,Zhang, An-Ling,Gao, Jin-Ming
, p. 2185 - 2190 (2015/02/05)
Cultivation of Penicillium minioluteum with azacitidine, a DNA methyltransferase inhibitor, led to the isolation of a novel type of aspertetronin dimer, named miniolins A-C (1-3), along with their precursor aspertetronin A (4). The structures of 1-3 were elucidated by extensive spectroscopic methods, and the absolute configurations were assigned by the chiral HPLC analysis of chemical degradation products and electronic circular dichroism associated with the TDDFT computational method (CAM-B3LYP/TZVP). The miniolins showed moderate cytotoxic activity against Hela cell lines. This journal is
Assembly and absolute configuration of short-lived polyketides from burkholderia thailandensis
Ishida, Keishi,Lincke, Thorger,Hertweck, Christian
supporting information; experimental part, p. 5470 - 5474 (2012/07/14)
Decoded before decay: Cryptic and highly unstable polyketide metabolites, thailandamidesA and B, were isolated from Burkholderia thailandensis, and their absolute configurations fully elucidated using a combination of chemical degradation, bioinformatics, NMR spectroscopy, precursor-directed biosynthesis, and analysis of pathway intermediates (see scheme). Copyright
THE TOTAL SYNTHESIS OF PIPTOSIDIN
Poss, A. J.,Smyth, M. S.
, p. 5469 - 5472 (2007/10/02)
The synthesis of piptosidin, 2a, by the Michael addition of ascorbic acid to tigloyl cyanide is reported.
