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36735-22-5

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36735-22-5 Usage

Description

Quazepam CIV (200 MG) is a benzodiazepine derivative drug that selectively binds to the benzodiazepine modulatory site on GABAA receptors with α1 subunit, acting as a hypnotic agent. It is known for its rapid action, short-term effectiveness, and low incidence of side effects. Quazepam is metabolized through oxidation, N-dealkylation, 3-hydroxylation, and glucuronidation, with its metabolites also being active. The brand name for Quazepam is Doral (Questcor).

Uses

Used in Pharmaceutical Industry:
Quazepam CIV (200 MG) is used as a hypnotic agent for the treatment of insomnia. It helps in inducing sleep, improving sleep quality, and reducing the time taken to fall asleep. Its selective action on GABAA receptors with α1 subunit contributes to its effectiveness in treating insomnia with minimal side effects.
Used in Sleep Aid Applications:
Quazepam CIV (200 MG) is used as a sleep aid for individuals experiencing difficulty in falling asleep or maintaining sleep. Its rapid onset and short-term action make it suitable for addressing sleep disturbances and improving overall sleep quality.
Used in Medical Treatment:
Quazepam CIV (200 MG) is used as a therapeutic agent in the management of insomnia and other sleep-related disorders. Its hypnotic properties and low side effect profile make it a preferred choice for healthcare professionals and patients seeking relief from sleep issues.

Originator

Schering (USA)

Check Digit Verification of cas no

The CAS Registry Mumber 36735-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,3 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 36735-22:
(7*3)+(6*6)+(5*7)+(4*3)+(3*5)+(2*2)+(1*2)=125
125 % 10 = 5
So 36735-22-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2

36735-22-5 Well-known Company Product Price

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  • USP

  • (1592205)  Quazepam  United States Pharmacopeia (USP) Reference Standard

  • 36735-22-5

  • 1592205-200MG

  • 5,736.51CNY

  • Detail

36735-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione

1.2 Other means of identification

Product number -
Other names Oniria

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:36735-22-5 SDS

36735-22-5Synthetic route

quazepam
36735-22-5

quazepam

[3H]-2-Oxoquazepam
49606-44-2

[3H]-2-Oxoquazepam

Conditions
ConditionsYield
With Hg(CH3COO)2 at 20℃; for 0.25h; pH 11.2 (Britton-Robinson buffer); 40percent DMF as solubilisator;100%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 10℃;50%
mercaptoacetic acid
68-11-1

mercaptoacetic acid

quazepam
36735-22-5

quazepam

10-chloro-7,11b-dihydro-11b-(2-fluorophenyl)-7-(2,2,2-trifluoro-ethyl)-thiazolo<3,2-d><1,4>benzodiazepin-3(2H)one-6(5H)thione

10-chloro-7,11b-dihydro-11b-(2-fluorophenyl)-7-(2,2,2-trifluoro-ethyl)-thiazolo<3,2-d><1,4>benzodiazepin-3(2H)one-6(5H)thione

Conditions
ConditionsYield
In benzene for 45h; Heating;42%

36735-22-5Upstream product

36735-22-5Downstream Products

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