37074-90-1

Basic information

• Product Name: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE
• Synonyms: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE;1,2,3,4-TETRA-O-ACETYL-6-O-TRIPHENYLMETHYL-BETA-D-GLUCOPYRANOSE;1,2,3,4-TETRA-O-ACETYL-6-O-TRITYL-BETA-D-GLUCOPYRANOSE;1,2,3,4-TETRAACETYL-6-O-TRITYL-BETA-D-GLUCOPYRANOSE;1,2,3,4-Tetra-O-acetyl-6-O-trityl-b-D-glucopyranose;6-TRITYL-1,2,3,4-TETRA-O-ACETYL-B-D-GLUCOSE;6-O-Trityl-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose;(2S,3R,4S,5R,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate
• CAS NO: 37074-90-1
• Molecular Formula: C₃₃H₃₄O₁₀
• Molecular Weight: 590.62
• Product Categories: Carbohydrates
• Mol File: 37074-90-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 165-166 °C
• Boiling Point: 633.3 °C at 760 mmHg
• Flash Point: 262.6 °C
• Appearance: /
• Density: 1.28 g/cm³
• CAS DataBase Reference: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE(37074-90-1)
• EPA Substance Registry System: 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE(37074-90-1)

Safety Data

• Hazardous Substances Data: 37074-90-1(Hazardous Substances Data)

Usage

General Description

6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE is a chemical compound with a complex molecular structure. It consists of four acetyl groups attached to a glucose molecule, along with a trityl group. 6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE is often used in organic synthesis and as a building block in the production of various pharmaceuticals and natural products. It is also utilized in chemical research and development due to its unique reactivity and potential application in the creation of new molecules.

Upstream product

• 50-99-7 D-glucose 
• 596-43-0 bromo-triphenyl-methane 
• 492-62-6 alpha-D-glucopyranose 
• 108-24-7 acetic anhydride 
• 54325-28-9 6-O-trityl-D-glucopyranose 
• 2280-44-6 D-Glucose 
• 76-83-5 trityl chloride 
• 54325-28-9 (2R,3R,4S,5S,6R)-6-Trityloxymethyl-tetrahydro-pyran-2,3,4,5-tetraol 
• 54325-28-9 6-O-trityl-α-D-glucose 

Downstream Products

• 22331-13-1 1,2,3,6-tetra-O-acetyl-4-O-benzyl-β-D-glucopyranose 
• 99337-73-2 1,2,3,6-tetra-O-acetyl-4-O-trityl-β-D-glucopyranose 
• 108257-55-2 1,2,3,4-tetra-O-acetyl-6-O-benzyl-β-D-glucopyranose 
• 6619-10-9 1,2,3,4-tetra-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranose 
• 4613-78-9 β-D-gentiobiose octaacetate 
• 124595-24-0 phenyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranoside 
• 324047-51-0 1,2,3,4-tetra-O-acetyl-6-O-[4-(10-undecenyloxy)benzoyl]-β-D-glucose 
• 13242-55-2 2,3,4-tri-O-acetyllevoglucosan 
• 27086-15-3 1,2,3,6-tetra-O-acetyl-β-D-glucopyranose 
• 13100-46-4 1,2,3,4-tetra-O-acetyl-β-D-glucopyranose 
• 5239-09-8 Neryl 2,3,4-tri-O-acetyl-6-O-(2,3,4-tri-O-acetyl-6-O-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 
• 80768-04-3 1,2,3,4-tetra-O-acetyl-6-O-(1,3,4,6-tetra-O-benzoyl-α-D-fructofuranosyl)-β-D-glucopyranose 
• 124595-23-9 phenyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl-1-thio-β-D-glucopyranoside 
• 14877-92-0 1,2,3,4-tetra-O-acetyl-6-O-(2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl)-β-D-glucopyranose 

Relevant articles and documents

Total synthesis of agalloside, isolated from: Aquilaria agallocha, by the 5-O-glycosylation of flavan

Agalloside (1) is a neural stem cell differentiation activator isolated from Aquilaria agallocha by our group using Hes1 immobilized beads. We conducted the first total synthesis of agalloside (1) via the 5-O-glycosylation of flavan 25 using glycosyl fluoride 20 in the presence of BF3·Et2O. Subsequent oxidation with DDQ to flavanone 2 and deprotection successively provided agalloside (1). This synthetic strategy holds promise for use in the synthesis of 5-O-glycosylated flavonoids. The synthesized agalloside (1) accelerated neural stem cell differentiation, which is a result comparable to that for the naturally occurring compound 1.

Synthesis of uniformly deuterated n-dodecyl-β -d-maltoside (d39 -DDM) for solubilization of membrane proteins in TROSY NMR experiments

This work reports the first synthesis of uniformly deuterated n-dodecyl-β -D-maltoside (d39-DDM). DDM is a mild non-ionic detergent often used in the extraction and purification of membrane proteins and for solubilizing them in experimental studies of their structure, dynamics and binding of ligands. We required d39-DDM for solubilizing large α-helical membrane proteins in samples for [15N-1H]TROSY (transverse relaxation-optimized spectroscopy) NMR experiments to achieve the highest sensitivity and best resolved spectra possible. Our synthesis of d39-DDM used d7-D-glucose and d25-n-dodecanol to introduce deuterium labelling into both the maltoside and dodecyl moieties, respectively. Two glucose molecules, one converted to a glycosyl acceptor with a free C4 hydroxyl group and one converted to a glycosyl donor substituted at C1 with a bromine in the α-configuration, were coupled together with an α(1 → 4) glycosidic bond to give maltose, which was then coupled with n-dodecanol by its substitution of a C1 bromine in the α-configuration to give DDM. 1H NMR spectra were used to confirm a high level of deuteration in the synthesized d39-DDM and to demonstrate its use in eliminating interfering signals from TROSY NMR spectra of a 52-kDa sugar transport protein solubilized in DDM.

Degradable polymer and process for production thereof

In one embodiment of the present invention, a degradable polymer having a peroxide bond therein is disclosed. The degradable polymer can be utilized in the fields of medicals or medical materials, can be applied to a DDS or gene delivery system, and can be used as a novel polymeric material or environmentally-friendly material. A polyperoxide, which is an alternating copolymer, has in a side chain thereof, a functional group (which is a substituent comprising a therapeutic molecule), a water-soluble substituent, or a biodegradable substituent.