37828-01-6

Basic information

• Product Name: 3,5-bis(chlorosulphonyl)benzoyl chloride
• Synonyms: 3,5-bis(chlorosulphonyl)benzoyl chloride;3,5-Bis(chlorosulfonyl)benzoyl chloride
• CAS NO: 37828-01-6
• Molecular Formula: C₇H₃Cl₃O₅S₂
• Molecular Weight: 337.58472
• EINECS: 253-678-7
• Mol File: 37828-01-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 486.3°Cat760mmHg
• Flash Point: 247.9°C
• Appearance: /
• Density: 1.784g/cm³
• Vapor Pressure: 1.31E-09mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: 3,5-bis(chlorosulphonyl)benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(chlorosulphonyl)benzoyl chloride(37828-01-6)
• EPA Substance Registry System: 3,5-bis(chlorosulphonyl)benzoyl chloride(37828-01-6)

Safety Data

• Hazardous Substances Data: 37828-01-6(Hazardous Substances Data)

Usage

Description

3,5-bis(chlorosulphonyl)benzoyl chloride is an organic compound with the chemical formula C7H2Cl2O4S2. It is a derivative of benzoyl chloride, featuring two chlorosulfonyl groups attached to the 3 and 5 positions of the benzene ring. 3,5-bis(chlorosulphonyl)benzoyl chloride is known for its reactivity and is commonly utilized in the synthesis of various organic compounds.

Uses

Used in Chemical Synthesis:
3,5-bis(chlorosulphonyl)benzoyl chloride is used as an intermediate in the chemical synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable building block in the creation of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,5-bis(chlorosulphonyl)benzoyl chloride is used as a key reactant in the synthesis of specific drug molecules. Its reactivity and functional groups enable the development of new therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Preparation of 3,5-Dichlorobenzoyl Chloride:
3,5-bis(chlorosulphonyl)benzoyl chloride is used as a precursor in the preparation of 3,5-dichlorobenzoyl chloride. 3,5-bis(chlorosulphonyl)benzoyl chloride is an important intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. The conversion of 3,5-bis(chlorosulphonyl)benzoyl chloride to 3,5-dichlorobenzoyl chloride involves the removal of the chlorosulfonyl groups, which can be achieved through various chemical reactions.

InChI:InChI=1/C7H3Cl3O5S2/c8-7(11)4-1-5(16(9,12)13)3-6(2-4)17(10,14)15/h1-3H

Upstream product

• 98-88-4 benzoyl chloride 

Downstream Products

• 2905-62-6 3,5-dichlorobenzoyl chloride 
• 918810-48-7 Methyl 3,5-bis(chlorosulfonyl)benzoate 
• 15501-48-1 5-(2-hydroxy-4-methyl-phenylcarbamoyl)-benzene-1,3-disulfonic acid 
• 108518-08-7 5-(3,5-bis-chlorosulfonyl-benzoylamino)-2-(2,4-di-tert-pentyl-phenoxy)-benzoic acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 
• 21829-31-2 3,5-bis-chlorosulfonyl-benzoic acid 
• 106421-35-6 5-(2-hydroxy-4-methyl-phenylcarbamoyl)-benzene-1,3-disulfonyl chloride 
• 89854-18-2 3,5-disulfamoyl-benzoic acid amide 
• 108799-61-7 4-chloro-1-hydroxy-[2]naphthoic acid-{4-[5-(3,5-bis-chlorosulfonyl-benzoylamino)-2-(2,4-di-tert-pentyl-phenoxy)-benzoylamino]-phenethylamide} 

Relevant articles and documents

A benzoyl chloride to the preparation of 3, 5 - dichloro benzoyl chloride (by machine translation)

The invention provides a process for preparing to benzoyl chloride for 3, 5 - dichloro benzoyl chloride method, the method is carried out in three steps, the reaction conditions are in the 50 - 150 °C, benzoyl chloride as the starting material by sulfonation, chlorinated, desulfurization to obtain 3, 5 - dichloro formyl chlorine thick, can be obtained through the rectification after the content is more than 99.5% target product 3, 5 - dichloro benzoyl chloride. The method not only raw material is simple and easy to obtain, by adding amides with the metal salt catalyst after the catalyst reaction temperature is greatly reduced, the whole no waste water is produced, exhaust gas HCl adopts the water absorbed to prepare hydrochloric acid, sulfur dioxide using 30% liquid caustic soda absorbed to prepare sodium sulfite, rectification stage only produces a small amount of solid residue, it is easy to realize industrial. (by machine translation)