38118-69-3

Basic information

• Product Name: Butanamide, 2-diazo-N-methyl-3-oxo-N-phenyl-
• CAS NO: 38118-69-3
• Molecular Formula: C11H11N3O2
• Molecular Weight: 217.227
• Mol File: 38118-69-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Butanamide, 2-diazo-N-methyl-3-oxo-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, 2-diazo-N-methyl-3-oxo-N-phenyl-(38118-69-3)
• EPA Substance Registry System: Butanamide, 2-diazo-N-methyl-3-oxo-N-phenyl-(38118-69-3)

Safety Data

• Hazardous Substances Data: 38118-69-3(Hazardous Substances Data)

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 941-55-9 4-toluenesulfonyl azide 
• 100-61-8 N-methylaniline 
• 2584-48-7 N-methyl-3-oxo-N-phenylbutanamide 
• 624-90-8 Methanesulfonyl azide 
• 186581-53-3 diazomethane 
• 1694-31-1 tert-butyl acetoacetate 

Downstream Products

• 38118-70-6 2-diazo-N-methyl-N-phenylacetamide 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 

Relevant articles and documents

Aqueous copper nitrate catalyzed synthesis of 3-alkylideneoxindoles from α-diazo-ketoanilides

An economical, practical, and green protocol with which to synthesize 3-alkylideneoxindoles from α-diazo-ketoanilides has been developed. The approach employs inexpensive Cu(NO3)2·3H 2O as catalyst and environmentally friendly water as solvent, and achieves moderate to excellent yields. The method has good tolerance to a range of N-alkyl and N-aryl groups, including electron-withdrawing and electron-donating groups on the aromatic ring, ortho-, meta-, and para-substituents, and -aliphatic and -aromatic keto groups. A plausible mechanism involving intramolecular aromatic metal carbene electrophilic addition as the key step is proposed. Inexpensive Cu(NO3)2· 3H2O catalyst and environmentally friendly water solvent are employed for the transformation of α-diazo-ketoanilides into 3-alkylidene- oxindoles. The process is easily handled, economical, environmentally friendly, and can be used to convert a broad range of substrates in moderate to excellent yields. An intramolecular aromatic metal carbene electrophilic addition mechanism is proposed. Copyright

Intramolecular hydrogen bonding-assisted cyclocondensation of α-diazoketones with various amines: A strategy for highly efficient Wolff 1,2,3-triazole synthesis

A catalytic and highly efficient Wolff's cyclocondensation of α-diazoketones with aromatic and aliphatic amines has been realized for the first time by utilizing the strategy of an intramolecular hydrogen bonding-activating carbonyl group. This approach successfully solved the challenging problem of poor condensation efficiency in Wolff 1,2,3-triazole synthesis, and constitutes a powerful method for the synthesis of highly functionalized 1,2,3-triazoles. The Royal Society of Chemistry 2012.

Rhodium(II)-catalyzed decomposition of β,γ-unsaturated diazo compounds

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