38129-46-3

Basic information

• Product Name: dimethyl β,β'-(2-phenylethylamino)dipropionate
• Synonyms: dimethyl β,β'-(2-phenylethylamino)dipropionate
• CAS NO: 38129-46-3
• Molecular Weight: 293.363
• Mol File: 38129-46-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: dimethyl β,β'-(2-phenylethylamino)dipropionate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl β,β'-(2-phenylethylamino)dipropionate(38129-46-3)
• EPA Substance Registry System: dimethyl β,β'-(2-phenylethylamino)dipropionate(38129-46-3)

Safety Data

• Hazardous Substances Data: 38129-46-3(Hazardous Substances Data)

Upstream product

• 40871-01-0 methyl 3-propionate 
• 292638-85-8 acrylic acid methyl ester 
• 64-04-0 phenethylamine 

Downstream Products

• 66670-11-9 methyl 1-(2-phenylethyl)-4-oxo-piperidine-3-carboxylate 
• 23808-42-6 1-(2-phenylethyl)-4-aminomethyl-4-piperidinol 
• 101745-47-5 4,4-diethoxy-1-phenethyl-piperidine 
• 95436-87-6 butyric acid-(1-phenethyl-4-phenyl-[4]piperidyl ester) 
• 64-50-6 propionic acid-(1-phenethyl-4-phenyl-[4]piperidyl ester) 
• 64-52-8 acetic acid-(1-phenethyl-4-phenyl-[4]piperidyl ester) 
• 109694-60-2 1-phenethyl-4-m-tolyl-piperidin-4-ol 
• 94913-96-9 1-phenethyl-4-phenyl-piperidin-4-ol 
• 39742-60-4 1-(2-phenylethyl)-4-piperidinone 

Relevant articles and documents

Two-step protic solvent-catalyzed reaction of phenylethylamine with methyl acrylate

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Nitro-Aldol Approach for Commercial Manufacturing of Fenspiride Hydrochloride

An efficient, short manufacturing process for fenspiride hydrochloride is reported. Nitro-aldol condensation is the key reaction in the developed process. Improved routes to key building blocks are demonstrated by expedient multikilogram production. Hazardous reactions are avoided. API produced following this new route meets the quality requirement NLT 99.70% purity by HPLC with any individual impurity NMT 0.10% with very good yield.

Novel symmetrical trans-bis-Schiff bases of N-substituted-4- piperidones: Synthesis, characterization, and preliminary antileukemia activity mensurations

A series of novel symmetrical trans-bis-Schiff bases (11a, 11b, 11c, 11d, 11e, 11f, 11g, 11h, 11i, 11j, 11k, 11l, 11m) were designed and prepared as novel anticancer analogues, with the trans-configuration confirmed by X-ray diffraction. Preliminary inhibitory effects of these compounds on CML K562 cell growth were investigated, and the potential analogue 11e showed an excellent anti-leukemia activity (IC50=6.35 μg/mL), which is higher than that of the clinical drug 5-fluorouracil (IC50=8.48 μg/mL). Complete assignments had been achieved for the title compounds by spectroscopic techniques, and their structure-activity relationships have been studied.