384355-71-9

Basic information

• Product Name: methyl phenyl acetylphosphonate
• Synonyms: methyl phenyl acetylphosphonate
• CAS NO: 384355-71-9
• Molecular Weight: 214.158
• Mol File: 384355-71-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl phenyl acetylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl phenyl acetylphosphonate(384355-71-9)
• EPA Substance Registry System: methyl phenyl acetylphosphonate(384355-71-9)

Safety Data

• Hazardous Substances Data: 384355-71-9(Hazardous Substances Data)

Upstream product

• 18351-42-3 dimethyl phenylphosphonite 
• 75-36-5 acetyl chloride 
• 108-95-2 phenol 
• 3426-89-9 phenyl phosphorodichloridite 

Downstream Products

• 347860-46-2 [1-(dimethoxyphosphonyl)-1-hydroxyethyl]-1-phosphonic acid methyl phenyl ester 

Relevant articles and documents

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and x-ray crystallography

The preparation and identification of symmetric, H3CC(OH)[P(O)(OR)2]2, where R=Me, Et, Pr1, Ph, and non-symmetric, H3CC(OH)[P(O)(OR1)(OR2)][P(O)(OR3)(O R4)], where R1=Me, R2=R3=R4=Ph; R1=R2=R3=Ph, R4=Me; R1=R3=Me, R2=R4=Ph; R1=R2=Et, Pr1, Ph and R3=R4=Me: tetraester derivatives of etidronate have been studied. Compounds were prepared from HP(O)(OR1)(OR2) and AcP(O)(OR3)(OR4) species under reflux. Mechanism studies have been made using HP(O)(OCD3)(OPh) and AcP(O)(OMe)(OPh) as starting materials. 1H, 13C, 31P NMR data and the MS fragmentation data in the gas phase are reported. The solid-state structures are given for three of the compounds, where R=Et, Ph and R1=R2=Ph, R3=R4=Me.