38583-51-6 Usage
Description
N-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide is a chemical compound characterized by its unique molecular structure, which features a thiazol ring with a methylsulfanyl group and an acetamide functional group. N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide has been studied for its potential biological activities and therapeutic applications.
Uses
Used in Pharmaceutical Industry:
N-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide is used as a potential therapeutic agent for its antidepressant and anxiolytic activity. N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide may help alleviate symptoms of depression and anxiety by modulating the neurotransmitters in the brain, leading to improved mood and reduced anxiety levels.
Check Digit Verification of cas no
The CAS Registry Mumber 38583-51-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,8 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 38583-51:
(7*3)+(6*8)+(5*5)+(4*8)+(3*3)+(2*5)+(1*1)=146
146 % 10 = 6
So 38583-51-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3OS2/c1-3(9)6-4-7-8-5(10-2)11-4/h1-2H3,(H,6,7,9)
38583-51-6Relevant articles and documents
Synthesis of 2-amino-5-sulfanyl-1,3,4-thiadiazole derivatives and evaluation of their antidepressant and anxiolytic activity
Clerici,Pocar,Guido,Loche,Perlini,Brufani
, p. 931 - 936 (2007/10/03)
Recently a series of 2-amino-5-sulfanyl-1,3,4-thiadiazole derivatives bearing different substituents were synthesized and screened pharmacologically in order to evaluate their central nervous system activity. The purpose of this study was to evaluate the effects of the title compounds on CNS activity by varying the substituents in the thiadiazole moiety. It was found that some of these compounds possess marked antidepressant and anxiolytic properties comparable in efficiency to the reference drugs Imipramine and Diazepam. The most potent compound 3k was further investigated to complete its pharmacological profile with respect to undesired side effects. Behavioral results showed that 3k is a very promising compound, characterized by a mixed antidepressant-anxiolytic activity accompanied by a therapeutic dose range that is essentially 2 orders of magnitude less than that at which side effects such as sedation and amnesia are evident.
