39088-05-6 Usage
Description
1,2-dihydro-4,6-dimethyl-2-oxonicotinamide is a chemical compound with the molecular formula C8H11NO2, derived from nicotinamide, a form of vitamin B3. It is a white crystalline solid that is soluble in water and has been studied for its potential pharmaceutical uses, including its ability to act as an antioxidant and protect against DNA damage caused by free radicals.
Uses
Used in Pharmaceutical Applications:
1,2-dihydro-4,6-dimethyl-2-oxonicotinamide is used as a potential therapeutic agent for various medical conditions due to its antioxidant properties and ability to protect against DNA damage caused by free radicals.
Used in Neurodegenerative Disease Treatment:
In the pharmaceutical industry, 1,2-dihydro-4,6-dimethyl-2-oxonicotinamide is used as a potential treatment for neurodegenerative diseases, leveraging its neuroprotective effects and ability to combat oxidative stress associated with such conditions.
Used in Cancer Therapy:
1,2-dihydro-4,6-dimethyl-2-oxonicotinamide is also being studied for its potential as a therapeutic agent in cancer treatment, where it may contribute to the mitigation of cancer progression and the enhancement of the effectiveness of other cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 39088-05-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,8 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 39088-05:
(7*3)+(6*9)+(5*0)+(4*8)+(3*8)+(2*0)+(1*5)=136
136 % 10 = 6
So 39088-05-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2/c1-4-3-5(2)10-8(12)6(4)7(9)11/h3H,1-2H3,(H2,9,11)(H,10,12)
39088-05-6Relevant articles and documents
The Kost-Sagitullin rearrangement in a series of 1-alkyl-2- (carbamoylmethyl)-4,6-dimethylpyrimidinium iodides
Danagulyan,Sahakyan
, p. 320 - 325 (2004)
The rearrangement of 1-alkyl-2-(carbamoylmethyl)pyrimidinium iodides into substituted 2-alkylaminonicotinamides occurring in alcoholic solutions of amines has been studied. It was shown that in the presence of water the rearrangement of 2-(carbamoylmethyl)-1,4,6-trimethylpyrimidinium iodide is accompanied by the formation of a derivative of 2-oxo-1,2-dihydronicotinic acid, and under the action of ethylamine a rearrangement and transamination occurs leading to 2-ethylamino-4,6-dimethylnicotinamide.
Synthesis and Photophysical Properties of 3-Amino-4-arylpyridin-2(1 H)-ones
Abramov, Anton A.,Chernenko, Sergey A.,Fisyuk, Alexander S.,Kostyuchenko, Anastasia S.,Shatsauskas, Anton L.
, p. 227 - 238 (2019/12/28)
A method has been developed for the preparation of oxazolo-[5,4- b ]pyridin-2(1 H)-ones based on the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides. Hydrolysis of oxazolo[5,4- b ]pyridin-2(1 H)-ones and the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides yielded 3-aminopyridin-2(1 H)-ones, including 4-aryl substituted derivatives in the series, for which effective phosphors with a quantum yield of up to 0.78 were detected. Photophysical properties of 3-aminopyridin-2(1 H)-ones were studied by UV and luminescence spectroscopy methods, and the relationship between their structure and photophysical properties was revealed.
