3959-08-8

Basic information

• Product Name: (phenylsulfinyl)acetic acid
• CAS NO: 3959-08-8
• Molecular Formula: C₈H₈O₃S
• Molecular Weight: 184.2123
• Mol File: 3959-08-8.mol
• Article Data: 36

Chemical Properties

• Boiling Point: 423°C at 760 mmHg
• Flash Point: 209.6°C
• Density: 1.43g/cm³
• Vapor Pressure: 6.54E-08mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: (phenylsulfinyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (phenylsulfinyl)acetic acid(3959-08-8)
• EPA Substance Registry System: (phenylsulfinyl)acetic acid(3959-08-8)

Safety Data

• Hazardous Substances Data: 3959-08-8(Hazardous Substances Data)

Usage

General Description

(Phenylsulfinyl)acetic acid is a chemical compound with the molecular formula C8H8O3S. It is a sulfinyl-containing compound that is used as a starting material in organic synthesis. (phenylsulfinyl)acetic acid has been studied for its potential use as a starting material in the synthesis of various biologically active pharmaceutical compounds. Its structure contains a phenyl group attached to a sulfinyl group, which gives it unique reactivity and potential applications in drug discovery and development. Additionally, (phenylsulfinyl)acetic acid has been investigated for its role in organic reactions and its potential use as a reagent in the synthesis of complex molecules.

Upstream product

• 108-98-5 thiophenol 
• 103-04-8 (phenylthio)acetic acid 
• 7732-18-5 water 
• 60-29-7 diethyl ether 
• 7647-01-0 hydrogenchloride 
• 7726-95-6 bromine 
• 7722-84-1 dihydrogen peroxide 

Downstream Products

• 103-04-8 (phenylthio)acetic acid 
• 3112-85-4 methylphenylsulfonate 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 1352703-53-7 tert-butyl 3-oxo-4-(phenylsulfinyl)-2-(triphenylphosphoranylidene)butanoate 
• 49639-34-1 phenylsulfinylacetic acid amide 
• 60178-25-8 ethyl α-chloro-α-(phenylthio)acetate 
• 108-98-5 thiophenol 
• 298-12-4 Glyoxilic acid 
• 79-14-1 glycolic Acid 
• 51416-91-2 α-chloro-α-phenylthioacetic acid 
• 3406-76-6 (4-bromophenylthio)acetic acid 
• 14090-83-6 methyl 2-phenylsulfinylacetate 

Relevant articles and documents

COMPOSITES, METHODS AND USES THEREOF

The present invention relates, in general terms, to methods of catalysing a reaction, including the steps of contacting a chemical entity comprising a sulphide moiety with a composite and an oxidant. The composite acts as a heterogeneous catalyst to oxidise the sulphide moiety. The present invention also relates to composites, methods of synthesising the composites and its use as a catalyst thereof.

Competitive behavior of nitrogen based axial ligands in the oxovanadium(IV)-salen catalyzed sulfoxidation of phenylmercaptoacetic acid

The sulfoxidation of twelve phenylmercaptoacetic acids (PMAA) by H2O2 catalyzed by three oxovanadium(IV)-salen complexes, having varied substituents on PMAA and salen with regard to their position, size and inductive effect, has been performed spectrophotometrically in 100percent acetonitrile medium. Three nitrogen bases (NB), pyridine (Py), imidazole (ImH) and 1-methylimidazole (MeIm), were used as axial ligands. It has been found that the rate of sulfoxidation is not only tuned by the substituents on PMAA and salen, but it is also varied by the addition of nitrogen bases. The observed order of retardation found among the different nitrogen bases is ImH > MeIm > Py. The rate of reaction decreases with the increase in concentration of the NB axial ligands. The strongly binding ImH shows the least reactivity. Hydroperoxovanadium(V)-salen has been proposed as the sole active oxidizing species. A detailed mechanistic study reveals that the low rate constant values in the presence of the nitrogen base is due to the existence of competition of NB with H2O2 and PMAA during the formation of active species and the coordination of PMAA with active species, respectively. Both electron donating and electron withdrawing substituents on PMAA retard the sulfoxidation rate significantly. The Hammett correlation between the rate constants and substituent constants shows a non-linear concave downward curve which is explained by the existence of two different rate determining steps within the same mechanism; coordination of PMAA with the active species for electron withdrawing substituents and transfer of oxygen to PMAA for electron donating substituents. All the experimental observations are explained by proposing a suitable mechanism.

Tungstate supported mesoporous silica SBA-15 with imidazolium framework as a hybrid nanocatalyst for selective oxidation of sulfides in the presence of hydrogen peroxide

In this work, a new heterogeneous catalyst (SBA-15/Im/WO4 2?) was prepared, and then its performance in the oxidation of organic sulfides was studied (using 30% H2O2 as green oxidant under neutral reaction conditions). This organic–inorganic hybrid mesoporous material was characterized by various techniques, such as FT-IR, inductively coupled plasma, X-ray powder diffraction, high-resolution-transmission electron microscopy, N2 adsorption–desorption and thermogravimetric analysis. The catalyst was also applied to the selective oxidation of various sulfides. The hybrid catalyst was easily recovered, and was very stable and retained good activity for at least five successive runs without any additional activation. Moreover, there was no remarkable decrease in the activity and selectivity of the catalyst. The products could be easily isolated by just removing the solvent after filtering the catalyst. The yields of the catalytic productions through this catalyst were in the range from 75% to 97%.