39711-79-0 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 39711-79-0 differently. You can refer to the following data:
1. white crystalline powder
2. N-ethyl-p-menthane-3-carboxamide is an odorless white, crystalline
solid. The compound has a strong and clear physiological cooling effect
and is used mainly in oral care products.
3. Slight menthol-like cooling effect aroma
Uses
Different sources of media describe the Uses of 39711-79-0 differently. You can refer to the following data:
1. WS 3 is a selective transient receptor potential melastatin-8 ligand.
2. Physiological coolant in foods, beverages, toiletries, cosmetics and pharmaceuticals.
Aroma threshold values
Aroma characteristics at 1.0%. Virtually odorless
Taste threshold values
Taste characteristics at 10 to 100 ppm. Intense lingering cooling. The cooling sensation builds slow but
steadily and grows to a lingering cooling mouthfeel with a slightly camphoraceous and minty character.
Flammability and Explosibility
Notclassified
Trade name
Winsense WS-3 (Renessenz)
Biological Activity
Cooling agent that is an agonist at TRPM8 receptors (EC 50 = 3.7 μ M).
Synthesis
0.89
g (0.0091 mol) of polyphosphoric acid (85%) and 0.42 g (0.0091 mol) of
ethanol were weighed. 0.54 g (0.0046 mol) of diethylcarbonate was added
dropwise slowly while cooling in an ice bath, wherein the temperature
increases slightly. After about 5 minutes, 0.5 g (0.0030 mol) of
p-menthane-3-carbonitrile was added. The reaction solution was heated
and stirred for 102 hours at 150°C. At the end of the reaction by GC,
about 70% of desired N-Ethyl-p-menthane-3-carboxamide was formed.Fig The synthetic method 1 of N-Ethyl-p-menthane-3-carboxamide
Check Digit Verification of cas no
The CAS Registry Mumber 39711-79-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,7,1 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 39711-79:
(7*3)+(6*9)+(5*7)+(4*1)+(3*1)+(2*7)+(1*9)=140
140 % 10 = 0
So 39711-79-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H25NO/c1-5-14-13(15)12-8-10(4)6-7-11(12)9(2)3/h9-12H,5-8H2,1-4H3,(H,14,15)/t10-,11+,12+/m0/s1
39711-79-0Relevant articles and documents
Composition having insect repellent characteristics
-
, (2008/06/13)
The present invention relates to a composition having effective insect repellent characteristics comprising as an active ingredient an N-substituted p-menthane carboxamide, which has little or no odor and which is substantially non-toxic for human, pet and livestock.