39739-01-0

Basic information

• Product Name: methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
• Synonyms: 2H-isoindole-2-propanoic acid, 1,3-dihydro-1,3-dioxo-, methyl ester
• CAS NO: 39739-01-0
• Molecular Formula: C₁₂H₁₁NO₄
• Molecular Weight: 233.22
• Mol File: 39739-01-0.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 367.5°C at 760 mmHg
• Flash Point: 176.1°C
• Density: 1.32g/cm³
• Vapor Pressure: 1.36E-05mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate(39739-01-0)
• EPA Substance Registry System: methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate(39739-01-0)

Safety Data

• Hazardous Substances Data: 39739-01-0(Hazardous Substances Data)

Usage

General Description

Methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate is a chemical compound used in the synthesis of pharmaceuticals and organic compounds. It is a derivative of isoindole and has a three-carbon chain with a methyl ester group. The compound has potential applications in the development of drugs and agrochemicals due to its structural properties and reactivity. It also has the potential to be used in the field of materials science for the synthesis of novel polymers and materials with specific properties. Overall, methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate is a versatile chemical with a wide range of potential applications in various industries.

Upstream product

• 136918-14-4 phthalimide 
• 292638-85-8 acrylic acid methyl ester 
• 67-56-1 methanol 
• 95349-09-0 vinyl β-phthalimidopropionate 
• 3485-84-5 N-vinylphthalimide 
• 201230-82-2 carbon monoxide 
• 107-31-3 Methyl formate 
• 50-00-0 formaldehyd 
• 64-18-6 formic acid 
• 3339-73-9 3-phthalimidopropanoic acid 

Downstream Products

• 3339-73-9 3-phthalimidopropanoic acid 
• 107-95-9 3-amino propanoic acid 

Relevant articles and documents

A convergent route to functional protected amines, diamines, and β-amino acids

Phthalimide protected amines react with NBS under peroxide initiation to give geminal phthalimido-bromo derivatives, which are readily converted into the corresponding xanthates. These xanthates in turn undergo radical additions to numerous olefins, provi

Green Esterification of Carboxylic Acids Promoted by tert-Butyl Nitrite

In this work, the green esterification of carboxylic acids promoted by tert-butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.

A general platinum-catalyzed alkoxycarbonylation of olefins

Hydroxy- and alkoxycarbonylation reactions constitute important industrial processes in homogeneous catalysis. Nowadays, palladium complexes constitute state-of-the-art catalysts for these transformations. Herein, we report the first efficient platinum-catalysed alkoxycarbonylations of olefins including sterically hindered and functionalized ones. This atom-efficient catalytic transformation provides straightforward access to a variety of valuable esters in good to excellent yields and often with high selectivities. In kinetic experiments the activities of Pd- and Pt-based catalysts were compared. Even at low catalyst loading, Pt shows high catalytic activity.