40463-09-0

Basic information

• Product Name: 4-methyl-1-phenylpentan-3-one
• Synonyms: 4-methyl-1-phenylpentan-3-one;1-Phenyl-4-methyl-3-pentanone;2-Methyl-5-phenyl-3-pentanone;4-Methyl-1-phenyl-3-pentanone
• CAS NO: 40463-09-0
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 254-930-9
• Mol File: 40463-09-0.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 254.8 °C at 760 mmHg
• Flash Point: 101 °C
• Appearance: /
• Density: 0.948 /cm³
• Vapor Pressure: 0.0169mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 4-methyl-1-phenylpentan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1-phenylpentan-3-one(40463-09-0)
• EPA Substance Registry System: 4-methyl-1-phenylpentan-3-one(40463-09-0)

Safety Data

• Hazardous Substances Data: 40463-09-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O/c1-10(2)12(13)9-8-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3

Upstream product

• 2021-28-5 ethyl dihydrocinnamate 
• 1068-55-9 isopropylmagnesium chloride 
• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 
• 60550-54-1 2-methyl-5-phenylpent-1-en-3-one 
• 79-31-2 isobutyric Acid 
• 501-52-0 3-Phenylpropionic acid 
• 68426-07-3 (+/-)-1-phenyl-5-methylpentan-3-ol 
• 40463-08-9 2,2-dimethyl-3-(2-phenylethyl)oxirane 
• 3277-89-2 phenethylmagnesium bromide 
• 25179-23-1 lithium dimethylacetate 
• 78-82-0 Isobutyronitrile 
• 90878-19-6 phenethylmagnesium chloride 
• 3160-32-5 4-methyl-1-phenyl-1-penten-3-one 
• 98611-98-4 N-(3-methylbutan-2-ylidene)-1-phenylmethanamine 

Downstream Products

• 260257-61-2 (RS)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid tert-butyl ester 
• 249728-38-9 4-hydroxy-6-isopropyl-6-phenethyl-5,6-dihydro-pyran-2-one 
• 20627-49-0 3-phenyl-propionic acid butyl ester 
• 68426-07-3 (+/-)-1-phenyl-5-methylpentan-3-ol 
• 1381772-25-3 (E)-1-(4-chlorophenyl)-2-(4-methyl-1-phenylpentan-3-ylidene)hydrazine 
• 1381772-21-9 (Z)-1-(4-chlorophenyl)-2-(4-methyl-1-phenylpentan-3-ylidene)hydrazine 
• 1381772-30-0 (E)-1-(4-methyl-1-phenylpentan-3-ylidene)-2-p-tolylhydrazine 
• 1381772-26-4 (Z)-1-(4-methyl-1-phenylpentan-3-ylidene)-2-p-tolylhydrazine 
• 23936-97-2 (±)2,4-dimethyl-1-phenylpentan-3-one 
• 263842-78-0 5-trifluoromethyl-pyridine-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-70-2 N-[5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-4-trifluoromethyl-benzenesulfonamide 
• 263842-71-3 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-3-cyano-benzenesulfonamide 
• 263842-72-4 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-4-cyano-benzenesulfonamide 
• 263842-75-7 pyridine-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 

Relevant articles and documents

Catalytic Radical Trifluoromethylalkynylation of Unactivated Alkenes

The trifluoromethylalkynylation of unactivated alkenes with alkynyl sulfones and Togni's reagent was developed. The reaction was catalyzed by 2,4,6-trimethylpyridine, leading to various β-trifluoromethylated alkynes under metal-free conditions with a broad substrate scope and wide functional group compatibility. A mechanism involving catalytic nonchain radical processes is proposed.

Visible-Light Decatungstate/Disulfide Dual Catalysis for the Hydro-Functionalization of Styrenes

We describe an efficient photoredox system, relying on decatungstate/disulfide catalysts, for the hydrofunctionalization of styrenes. In this methodology the use of disulfide as a cocatalyst was shown to be crucial for the reaction efficiency. This photoredox system was employed for the hydro-carbamoylation, -acylation, -alkylation, and -silylation of styrenes, giving access to a large variety of useful building blocks and high-value molecules such as amides and unsymmetrical ketones from simple starting materials.

Preparation of 2-Arylquinolines from 2-Arylethyl Bromides and Aromatic Nitriles with Magnesium and N -Iodosuccinimide

Treatment of 2-arylethylmagnesium bromides, prepared from 2-arylethyl bromides and magnesium, with aromatic nitriles, followed by reaction with water and then with N -iodosuccinimide under irradiation with a tungsten lamp, gave the corresponding 2-arylquinolines in good to moderate yields under transition-metal-free conditions. 2-Alkylquinolines could be also obtained in moderate yields by the same procedure with 2-arylethyl bromides, magnesium, aliphatic nitriles bearing a secondary alkyl group, and N -iodosuccinimide.