41780-79-4

Basic information

• Product Name: N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide
• Synonyms: N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide
• CAS NO: 41780-79-4
• Molecular Weight: 299.353
• Mol File: 41780-79-4.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide(41780-79-4)
• EPA Substance Registry System: N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide(41780-79-4)

Safety Data

• Hazardous Substances Data: 41780-79-4(Hazardous Substances Data)

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 70135-28-3 (4-cyanophenyl)diazomethane 
• 5216-37-5 (E)-4,4'-dicyanostilbene 
• 104-85-8 para-methylbenzonitrile 
• 1566469-69-9 (E)-4-(3,3,3-trifluoro-2-phenylprop-1-en-1-yl)benzonitrile 
• 1566470-36-7 C₁₆H₁₀F₃N₃ 
• 1566469-71-3 (Z)-4-(3,3,3-trifluoro-2-phenylprop-1-enyl)benzonitrile 
• 27973-41-7 4-((9H-fluoren-9-ylidene)methyl)benzonitrile 
• 27980-53-6 4-((9H-xanthen-9-ylidene)methyl)benzonitrile 
• 74261-28-2 4-(2-(4-methoxyphenyl)cyclopropyl)benzonitrile 
• 23450-31-9 4-benzylbenzonitrile 
• 69922-33-4 C₁₅H₁₅N₃O₂S 

Relevant articles and documents

CuI-catalyzed cross-coupling of N-tosylhydrazones with terminal alkynes: Synthesis of 1,3-disubstituted allenes

A CuI-catalyzed synthesis of 1,3-disubstituted allenes from 1-alkynes by the reaction with various N-tosylhydrazones has been developed. This method, which uses readily available starting materials and is operationally simple, offers 1,3-disubstituted all

Iron Hydride Radical Reductive Alkylation of Unactivated Alkenes

Iron-catalyzed hydrogen atom transfer-mediated intermolecular C-C coupling reactions between alkenes and tosylhydrazones, followed by in situ cleavage of the tosylhydrazine intermediates using Et3N, are described. The process involves a new strategic bond disconnection resulting in the reductive alkylation of nonactivated alkenes. The reaction is operationally simple, proceeds under mild conditions, and has a wide substrate scope.

One-Pot Reaction between N-Tosylhydrazones and 2-Nitrobenzyl Bromide: Route to NH-Free C2-Arylindoles

A one-pot Barluenga coupling between N-tosylhydrazones and nitro-benzyl bromide, followed by deoxygenation of ortho-nitrostyrenes, and subsequent cyclization has been developed, providing a new way to synthesize various C2-arylindoles. This method exhibits a good substrate scope and functional group tolerance, and it allows an access to NH-free indoles, which can present a potential utility in medicinal chemistry applications.