4541-35-9

Basic information

• Product Name: 2,2,5,5-TETRAMETHYLCYCLOPENTANONE
• Synonyms: 2,2,5,5-TETRAMETHYLCYCLOPENTANONE;2,2,5,5-tetramethylcyclopentan-1-one
• CAS NO: 4541-35-9
• Molecular Formula: C₉H₁₆O
• Molecular Weight: 140.22
• Mol File: 4541-35-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 172.1°Cat760mmHg
• Flash Point: 51°C
• Appearance: /
• Density: 0.865g/cm³
• Vapor Pressure: 1.35mmHg at 25°C
• Refractive Index: 1.429
• CAS DataBase Reference: 2,2,5,5-TETRAMETHYLCYCLOPENTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,5,5-TETRAMETHYLCYCLOPENTANONE(4541-35-9)
• EPA Substance Registry System: 2,2,5,5-TETRAMETHYLCYCLOPENTANONE(4541-35-9)

Safety Data

• Hazardous Substances Data: 4541-35-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 859, 1990 DOI: 10.1016/S0040-4039(00)94647-1

InChI:InChI=1/C9H16O/c1-8(2)5-6-9(3,4)7(8)10/h5-6H2,1-4H3

Upstream product

• 1120-72-5 2-Methylcyclopentanone 
• 74-88-4 methyl iodide 
• 143142-54-5 3,5-dimethyl-4-<(2,2,5,5-tetramethylcyclopentylidene)amino>aniline 

Downstream Products

• 1000-30-2 2,2,5-trimethyl-4-hexenal 
• 129603-27-6 2,2,5,5-tetramethyl-1-(phenylselenomethyl)cyclopentanol 
• 70302-23-7 2,2,5,5-tetramethylcyclopentanone (triphenylphosphoranylidene)hydrazone 
• 15587-83-4 2,2,5,5-tetramethylcyclopent-1-yl p-toluenesulfonate 
• 15189-14-7 2,2,5,5-tetramethylcyclohexanone 
• 50876-33-0 1,1,3,3-tetramethyl-cyclopentane 

Relevant articles and documents

Highly regioselective alkylation at the more hindered α-site of unsymmetrical ketones by use of their potassium enolates. A comparative study with lithium enolates

Alkylation of regioisomeric potassium enolates 4 and 6 obtained from corresponding silyl enol ethers 2 and 3 occurs at the most substituted site affording ketones 8. Alkylation of corresponding lithium enolates 5 and 7 occurs at the expected site affording ketones 8 or 9. As an application the one pot synthesis of spiroketones 13 from silyl enol ethers 12 is described.