457631-44-6Relevant articles and documents
METHOD FOR CLEAVING AMIDE BONDS
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, (2019/01/25)
A method for cleaving amide bonds, comprising: a) providing a molecule comprising an amide group;b) reacting the molecule comprising an amide group with hydroxylamine (NH2OH) or a salt thereof to cleave the amide bond of the amide group.
A method of preparing P ethylamine
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Paragraph 0059; 0060; 0061, (2017/04/14)
The invention discloses a preparation method of p-aminophenylethylamine, belonging to the technical field of organic synthesis. The technical scheme is as follows: the preparation method comprises the following steps: by using p-nitrophenylethanol as a raw material, carrying out catalytic hydrogenation to reduce the para-position nitro groups of the p-nitrophenylethanol into amino groups, carrying out Boc acid anhydride protection on the para-position nitro groups, carrying out substitution reaction on hydroxy groups with sulfonyl chloride compounds to obtain sulfonic acid compounds, aminating, and finally, removing Boc groups to obtain the p-aminophenylethylamine. The preparation process is simple and easy to implement, and has the advantages of cheap and accessible raw materials, higher reaction efficiency and favorable repetitiveness.
NOVEL PROCESS FOR PREPARATION OF MIRABEGRON AND IT'S INTERMEDIATE
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, (2015/11/10)
The present invention related to a novel process for preparation of Mirabegron of formula (I) and its intermediate. I