466694-48-4

Basic information

• Product Name: methyl 3-(Z)-[1-{4-[(2-dimethylamino-ethyl)-carbamoyl]-phenylamino}-1-phenyl-methylidene]-2-indolinone-6-carboxylate
• CAS NO: 466694-48-4
• Molecular Weight: 484.555
• Mol File: 466694-48-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-(Z)-[1-{4-[(2-dimethylamino-ethyl)-carbamoyl]-phenylamino}-1-phenyl-methylidene]-2-indolinone-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(Z)-[1-{4-[(2-dimethylamino-ethyl)-carbamoyl]-phenylamino}-1-phenyl-methylidene]-2-indolinone-6-carboxylate(466694-48-4)
• EPA Substance Registry System: methyl 3-(Z)-[1-{4-[(2-dimethylamino-ethyl)-carbamoyl]-phenylamino}-1-phenyl-methylidene]-2-indolinone-6-carboxylate(466694-48-4)

Safety Data

• Hazardous Substances Data: 466694-48-4(Hazardous Substances Data)

Upstream product

• 1168152-06-4 (E)-1-acetyl-3-(ethoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester 
• 188758-93-2 N-<2-(dimethylamino)ethyl>-4-aminobenzamide 

Relevant articles and documents

Substituted indolinones

The present invention relates to indolinones substituted in the 6-position of general formula wherein R1 to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various, pharmaceutical compositions containing these compounds, their use and processes for preparing them.