475467-02-8 Usage
Description
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER, also known as propargyl-keto-phosphonate, is a chemical compound with the molecular formula C9H15O4P. It is a white crystalline powder that is soluble in organic solvents such as ethanol and acetone. This versatile compound is commonly used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER is used as a building block for the preparation of various agrochemicals, aiding in the creation of new pesticides and other agricultural chemicals.
Used in Organic Synthesis:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER is used as a reagent for the synthesis of various heterocyclic compounds, playing a crucial role in the development of complex organic molecules.
Used in Organometallic Chemistry:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER is used as a ligand for the formation of coordination complexes in organometallic chemistry, enabling the creation of new metal complexes with potential applications in various fields.
Used in Material Science:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER has potential applications in the development of new materials, where its unique properties can be harnessed to create innovative and advanced materials.
Used in Organic and Inorganic Transformations:
(2-OXOOCT-6-YNYL)PHOSPHONIC ACID DIMETHYL ESTER is used as a reagent in organic and inorganic transformations, facilitating various chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 475467-02-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,4,6 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 475467-02:
(8*4)+(7*7)+(6*5)+(5*4)+(4*6)+(3*7)+(2*0)+(1*2)=178
178 % 10 = 8
So 475467-02-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H17O4P/c1-4-5-6-7-8-10(11)9-15(12,13-2)14-3/h6-9H2,1-3H3
475467-02-8Relevant articles and documents
Formal synthesis of palmerolide A, featuring alkynogenic fragmentation and syn-selective vinylogous aldol chemistry
Lisboa, Marilda P.,Jones, David M.,Dudley, Gregory B.
, p. 886 - 889 (2013/04/10)
An enantioselective route to palmerolide A is described. The approach features original syntheses of three subunits, which are then assembled to produce a known late-stage intermediate and formally provide the highest overall yield of the natural product
Ring opening of cyclic vinylogous acyl triflates using stabilized carbanion nucleophiles: Claisen condensation linked to carbon-carbon bond cleavage
Jones, David M.,Lisboa, Marilda P.,Kamijo, Shin,Dudley, Gregory B.
experimental part, p. 3260 - 3267 (2010/08/19)
Addition of stabilized carbanionic nucleophiles to cyclic vinylogous acyl triflates (VATs) triggers a ring-opening fragmentation to give acyclic β-keto ester and related products, much like those observed traditionally in the Claisen condensation. Unlike in the classical Claisen condensation, however, the VAT-Claisen reaction described herein is rendered irreversible by C-C bond cleavage, not by deprotonation of the activated methylene product. Full details of this original reaction methodology are disclosed herein, including how subtle differences between the various nucleophiles impact the proper choice of reaction conditions for making 1,3-diketones, β-keto esters, and β-keto phosphonates.
Claisen-type condensation of vinylogous acyl triflates
Kamijo, Shin,Dudley, Gregory B.
, p. 175 - 177 (2007/10/03)
(Chemical Equation Presented) The Claisen-type condensation reaction of cyclic vinylogous carboxylic acid triflates with lithium enolates and their analogues produces acyclic alkynes bearing a 1,3-diketone-type moiety. The present transformation is proposed to proceed via a 1,2-addition of the enolate to the vinylogous acyl triflate, followed by fragmentation of the aldolate intermediate.