477709-06-1

Basic information

• Product Name: 1-METHYL-N-(4-METHYL-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE
• Synonyms: 1-methyl-N-(4-methylpyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide;1-METHYL-N-(4-METHYL-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE
• CAS NO: 477709-06-1
• Molecular Formula: C12H11F3N4O
• Molecular Weight: 284.24
• Mol File: 477709-06-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYL-N-(4-METHYL-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-N-(4-METHYL-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE(477709-06-1)
• EPA Substance Registry System: 1-METHYL-N-(4-METHYL-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE(477709-06-1)

Safety Data

• Hazardous Substances Data: 477709-06-1(Hazardous Substances Data)

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 126674-98-4 1-methyl-3-trifluoromethyl-1H-pyrazole-4-carbonyl chloride 
• 113100-53-1 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid 
• 571-55-1 ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate 
• 111493-74-4 ethyl 3-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate 
• 155377-19-8 ethyl 3-trifluoromethyl-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Synthesis and antifungal activity of n-(substituted pyridinyl)- 1-methyl(phenyl)-3-(trifluoromethyl)-1h-pyrazole-4- carboxamide derivatives

A series of N-(substituted pyridinyl)-1-methyl(phenyl)-3-trifluoromethyl- 1Hpyrazole- 4-carboxamide derivatives were synthesized. All target compounds were characterized by spectral data (1H-NMR, 13C-NMR, IR, MS) and elemental analysis and were bioassayed in vitro against three kinds of phytopathogenic fungi (Gibberella zeae, Fusarium oxysporum, Cytospora mandshurica). The results showed that some of the synthesized N-(substituted pyridinyl)-1-methyl-3- trifluoromethyl-1H-pyrazole-4-carboxamides exhibited moderate antifungal activities, among which compounds 6a, 6b and 6c displayed more than 50% inhibition activities against G. zeae at 100 μg/mL, which was better than that of the commercial fungicides carboxin and boscalid.