478028-43-2

Basic information

• Product Name: 2H-Thieno[3,2-d][1,3]oxazine-2,4(1H)-dione, 6-phenyl-
• CAS NO: 478028-43-2
• Molecular Formula: C12H7NO3S
• Molecular Weight: 245.258
• Mol File: 478028-43-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2H-Thieno[3,2-d][1,3]oxazine-2,4(1H)-dione, 6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Thieno[3,2-d][1,3]oxazine-2,4(1H)-dione, 6-phenyl-(478028-43-2)
• EPA Substance Registry System: 2H-Thieno[3,2-d][1,3]oxazine-2,4(1H)-dione, 6-phenyl-(478028-43-2)

Safety Data

• Hazardous Substances Data: 478028-43-2(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 100063-22-7 methyl 3-amino-5-phenylthiophene-2-carboxylate 
• 99972-47-1 3-amino-5-phenyl-2-thiophenecarboxylic acid 
• 98-86-2 acetophenone 
• 78583-84-3 3-chloro-3-phenylprop-2-enenitrile 

Relevant articles and documents

Synthesis and combinatorial approach of the reactivity of 6- and 7-arylthieno[3,2-d][1,3]oxazine-2,4-diones

This paper describes a general procedure for the synthesis of new substituted thiaisatoic anhydrides or 6- or 7-aryl-1H-thiéno[3,2-d][1,3] oxazine-2,4-diones 3a-j and 4a-f. They were synthesized in large scale under microwave heating conditions with high yields. The reactivity vs nucleophilic reagents of these compounds was studied and permitted to develop a simple combinatorial procedure to synthesize a library of new thiophene ureidoacids 7a-j and 8a-j.

Novel small molecule inhibitors targeting the "switch region" of bacterial RNAP: Structure-based optimization of a virtual screening hit

Rising resistance against current antibiotics necessitates the development of antibacterial agents with alternative targets. The "switch region" of RNA polymerase (RNAP), addressed by the myxopyronins, could be such a novel target site. Based on a hit can

Anti-infective agents

Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.