4810-42-8 Usage
Description
N,N-diethylpyridine-3-sulfonamide, commonly known as DEET, is a widely used insect repellent that offers effective protection against mosquito and tick bites. It operates by blocking the insects' olfactory receptors, which makes it challenging for them to locate and feed on the skin. DEET is available in various forms, including lotions, sprays, and wipes, and is considered safe for use when following label instructions. Although there have been concerns regarding its potential health and environmental effects, studies have demonstrated that DEET is generally safe for human use and does not present significant risks when used in the recommended doses. DEET is a valuable resource for preventing insect-borne diseases and ensuring protection in outdoor settings.
Uses
Used in Insect Repellent Applications:
N,N-diethylpyridine-3-sulfonamide is used as an insect repellent for preventing mosquito and tick bites. It serves to block the insects' olfactory receptors, making it difficult for them to locate and feed on the skin, thereby providing protection against insect-borne diseases.
Used in Outdoor Protection:
N,N-diethylpyridine-3-sulfonamide is used as a protective agent in outdoor settings to safeguard individuals from the bites of insects that may carry diseases. By applying DEET in the recommended forms such as lotions, sprays, and wipes, people can enjoy outdoor activities with reduced risk of insect bites.
Check Digit Verification of cas no
The CAS Registry Mumber 4810-42-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,1 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4810-42:
(6*4)+(5*8)+(4*1)+(3*0)+(2*4)+(1*2)=78
78 % 10 = 8
So 4810-42-8 is a valid CAS Registry Number.
4810-42-8Relevant articles and documents
Nucleophilic C-H Etherification of Heteroarenes Enabled by Base-Catalyzed Halogen Transfer
Puleo, Thomas R.,Klaus, Danielle R.,Bandar, Jeffrey S.
supporting information, p. 12480 - 12486 (2021/08/24)
We report a general protocol for the direct C-H etherification of N-heteroarenes. Potassium tert-butoxide catalyzes halogen transfer from 2-halothiophenes to N-heteroarenes to form N-heteroaryl halide intermediates that undergo tandem base-promoted alcohol substitution. Thus, the simple inclusion of inexpensive 2-halothiophenes enables regioselective oxidative coupling of alcohols with 1,3-azoles, pyridines, diazines, and polyazines under basic reaction conditions.
Efficient and scalable synthesis of pyridine sulfonamides
Emura, Takashi,Yoshino, Hitoshi,Tachibana, Kazutaka,Shiraishi, Takuya,Honma, Akie,Mizutani, Akemi,Muraoka, Terushige
experimental part, p. 1117 - 1120 (2011/06/20)
Short-step and scalable transformations from 2,6-dibromopyridine to 6-bromopyridine-2-sulfonamide by means of halogen-metal exchange and subsequent reaction with sulfuryl chloride followed by amidation are established. Application of the method for the synthesis of various pyridine sulfonamides is also described. Georg Thieme Verlag Stuttgart - New York.
Facile one-pot synthesis of aromatic and heteroaromatic sulfonamides
Pandya, Rina,Murashima, Takashi,Tedeschi, Livio,Barrett, Anthony G. M.
, p. 8274 - 8276 (2007/10/03)
A series of arene and heteroarene sulfonamides were prepared in one vessel from aryl and heteroaryl bromides via conversion into the corresponding Grignard reagents using either magnesium or isopropylmagnesium chloride and subsequent reaction with sulfur dioxide, sulfuryl chloride, and an amine.
