5042-30-8 Usage
Description
2,2,2-Trifluoroethylhydrazine is an organic compound with the chemical formula C2H5F3N2. It is characterized by the presence of a trifluoromethyl group (CF3) attached to an ethyl group (C2H5) and two hydrazine (NH2) groups. This unique structure endows it with specific chemical properties and reactivity, making it suitable for various applications in different fields.
Uses
Used in Biochemical Research:
2,2,2-Trifluoroethylhydrazine is used as a reagent in biochemical research for studying the interaction of heme proteins, such as myoglobin. Its addition to myoglobin allows researchers to investigate the binding and functional changes that occur upon interaction, providing insights into the structure and function of these important proteins.
Used in Analytical Chemistry:
In the field of analytical chemistry, 2,2,2-trifluoroethylhydrazine is employed as a selective and sensitive reagent for the simultaneous determination of aldehydes and acetone in water. Its ability to react specifically with these compounds enables the development of analytical methods for their detection and quantification, which is crucial for monitoring water quality and assessing the presence of potentially harmful substances.
Check Digit Verification of cas no
The CAS Registry Mumber 5042-30-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,4 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5042-30:
(6*5)+(5*0)+(4*4)+(3*2)+(2*3)+(1*0)=58
58 % 10 = 8
So 5042-30-8 is a valid CAS Registry Number.
InChI:InChI=1/C2H7F3N2/c3-2(4,5)1-7-6/h1,7H2,6H3/q+2
5042-30-8Relevant articles and documents
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators
Sharma, Swagat,Kozek, Krystian A.,Abney, Kristopher K.,Kumar, Sushil,Gautam, Nagsen,Alnouti, Yazen,David Weaver,Hopkins, Corey R.
, p. 791 - 796 (2019/02/06)
The present study describes the discovery and characterization of a series of 5-aryl-2H-tetrazol-3-ylacetamides as G protein-gated inwardly-rectifying potassium (GIRK) channels activators. Working from an initial hit discovered during a high-throughput screening campaign, we identified a tetrazole scaffold that shifts away from the previously reported urea-based scaffolds while remaining effective GIRK1/2 channel activators. In addition, we evaluated the compounds in Tier 1 DMPK assays and have identified a (3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene-1,1-dioxide head group that imparts interesting and unexpected microsomal stability compared to previously-reported pyrazole head groups.