50594-94-0

Basic information

• Product Name: Methanol, chloro-, carbonate (2:1)
• CAS NO: 50594-94-0
• Molecular Formula: C3H4Cl2O3
• Molecular Weight: 158.969
• Mol File: 50594-94-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanol, chloro-, carbonate (2:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Methanol, chloro-, carbonate (2:1)(50594-94-0)
• EPA Substance Registry System: Methanol, chloro-, carbonate (2:1)(50594-94-0)

Safety Data

• Hazardous Substances Data: 50594-94-0(Hazardous Substances Data)

Usage

General Description

Methanol, chloro-, carbonate (2:1) is a chemical compound formed by the combination of one molecule of methanol and two molecules of chloroform. It has the formula CH3OH?2CHCl3 and is commonly used in organic synthesis and as a solvent in various industrial processes. Methanol, chloro-, carbonate (2:1) is a colorless, flammable liquid with a sweet odor, and is considered highly toxic and potentially harmful to human health. It is also an environmental hazard, as it can contaminate water and soil and is not readily biodegradable. Therefore, proper handling and disposal of this chemical is necessary to prevent harm to both human health and the environment.

Upstream product

• 616-38-6 carbonic acid dimethyl ester 
• 22128-62-7 carbonochloridic acid, chloromethyl ester 
• 58-22-0 testosterone 

Downstream Products

• 215927-11-0 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-(3-chloromethoxycarbonyloxymethyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 143588-03-8 1-t-butoxycarbonyl-4-hydroxy-3-(N-methoxycarbonyl-N-methyl)aminopyrrolidine 
• 84756-61-6 iodomethyl carbonate 

Relevant articles and documents

Compositions and methods for enhanced drug delivery

The present invention relates to methods of delivering pharmaceutical agents across membranes, including the skin layer or mucosal membranes of a patient. A pharmaceutical agent is covalently bonded to a chemical modifier, via a physiologically cleavable bond, such that the membrane transport and delivery of the agent is enhanced.

Cleavage of carbon-sulfur bonds in the synthesis of α-haloalkyl carbonates

α-Chloroalkyl and α-bromoalkyl carbonates have been prepared by cleavage of α-arylthioalkyl carbonates with sulfuryl chloride or bromine, respectively. The α-arylthioalkyl carbonates are prepared by reaction of the hemithioacetal 1 with chloroformates or by a destannylative tin-Pummerer rearrangement of α-stannyl sulfoxides. Acta Chemica Scandinavica 1996.