50672-13-4

Basic information

• Product Name: 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid
• Synonyms: 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid
• CAS NO: 50672-13-4
• Molecular Weight: 190.242
• Mol File: 50672-13-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid(50672-13-4)
• EPA Substance Registry System: 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid(50672-13-4)

Safety Data

• Hazardous Substances Data: 50672-13-4(Hazardous Substances Data)

Usage

General Description

2,2-dimethyl-3-phenylcyclopropanecarboxylic acid is a cyclic carboxylic acid compound with a unique structure. It contains a cyclopropane ring attached to a phenyl group and a carboxyl group. The presence of the dimethyl substituents on the cyclopropane ring and the phenyl group gives this compound its distinct properties. This chemical may have potential applications in pharmaceuticals, agrochemicals, and materials science due to its unique structural features and potential reactivity. Further research and studies are needed to explore its potential uses and properties.

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 768-49-0 (2-methyl-1-propenyl)-benzene 
• 4192-77-2 ethyl cinnamate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 61751-36-8 (±)-trans-ethyl 2,2-dimethyl-3-phenylcyclopropanecarboxylate 
• 99647-67-3 2,2-dimethyl-3-phenyl-cyclopropanecarbonitrile 
• 105640-04-8 4,4-dimethyl-5-phenyldihydrofuran-2(3H)-one 
• 93085-88-2 (+/-)-trans-2,2-dimethyl-3-phenylcyclopropanecarboxamide 
• 61751-36-8 2,2-Dimethyl-3-phenyl-cyclopropan-carbonsaeure-⁽¹⁾-ethylester 

Downstream Products

• 494846-57-0 (-)-trans-(1S,3S)-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 4489-17-2 (+/-)-2,2-dimethyl-3t-phenyl-cyclopropane-r-carbonyl chloride 
• 93085-88-2 (+/-)-2,2-dimethyl-3c-phenyl-cyclopropane-r-carboxylic acid amide 
• 157240-02-3 methyl (1S,3S)-2,2-dimethyl-3-phenylcyclopropanecarboxylate 
• 494846-26-3 (+)-trans-(1R,3R)-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 1557243-20-5 (1R,3R)-N-[5-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-2,2-dimethyl-3-phenylcyclopropanecarboxamide 
• 1610023-35-2 C₁₂H₁₃ClO 
• 78003-28-8 trans-2,2-Dimethyl-3-(4-brom-phenyl)-cyclopropan-carbonsaeure-⁽¹⁾ 

Relevant articles and documents

ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF

Disclosed are compounds of Formula (IVA), or a salt thereof, and pharmaceutical formulations (pharmaceutical compositions) comprising those compounds, or a salt thereof: Formula (IVA), wherein "RIa", "RIb", "RIc", "RId", "RIe", are defined herein above, which compounds are believed suitable for use in positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR) receptors, for example, those found in the cerebral cortex and the hippocampus. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Alzheimer's disease (AD), schizophrenia, and Parkinson's disease (PD), or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.

N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS

The invention provides novel substituted cyclopropane carboxamide compounds according to Formula (I), their manufacture and use for the treatment of proliferative inflammatory diseases, such as cancer, fibrosis or arthritis.

A TANDEM MICHAEL REACTION-CYCLOALKYLATION UTILIZING 2-NITROPROPANE: A FACILE ROUTE TO THE ACID COMPONENT OF INSECTICIDAL PYRETHROIDS

Treatment of three representative β-substituted-α-cyanoacrylates (2) with 2-nitropropane and potassium carbonate in refluxing ethanol afforded stereoselectively cyclopropanoid precursors (4) to 3-substituted-2,2-dimethylcyclopropanecarboxylic acids (7).