50846-45-2 Usage
Originator
Bacmecillinam,ZYF Pharm Chemical
Manufacturing Process
1-Hexamethyleneiminocarboxaldehyde dimethylacetate (3.1 g) in chloroform
(50 ml) was added dropwise at -30°C to a solution of 1’-
ethoxycarbonyloxyethyl 6-aminopenicillanate (5.0 g) and triethylamine (1.9
ml) in chloroform (150 ml) during 15 min. Then, the temperature is allowed
to rise to 0°C during 30 min, and the mixture is stirred at 0°C for another 60
min. Water (120 ml) is added, and stirring is continued for 10 min. The water
phase is separated and the organic layer is washed with water and stripped.
There was obtained 5.0 g of the 1’-ethoxycarbonyloxy-ethyl 6-(hexahydro-1Hazepin-
l-yl) methyleneaminopenicillanate.
Therapeutic Function
Antibiotic
Safety Profile
An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx and NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 50846-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,8,4 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 50846-45:
(7*5)+(6*0)+(5*8)+(4*4)+(3*6)+(2*4)+(1*5)=122
122 % 10 = 2
So 50846-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H31N3O6S/c1-5-27-19(26)29-13(2)28-18(25)15-20(3,4)30-17-14(16(24)23(15)17)21-12-22-10-8-6-7-9-11-22/h12-15,17H,5-11H2,1-4H3/b21-12+/t13?,14-,15+,17-/m1/s1
50846-45-2Relevant articles and documents
Esters of amidinopenicillanic acids, pharmaceutical preparations and method for treating infectious diseases
-
, (2008/06/13)
New esters of amidinopenicillanic acids of the formula STR1 wherein each of R1 and R2, which are the same or different, is a saturated or unsaturated alkyl group, a cycloalkyl, or cycloalkyl-alkyl group, or wherein R1 and R2, together with the adjacent nitrogen atom, form a heterocyclic ring system; R3 is the radical STR2 in which radicals R4 is an alkyl, phenyl, or substituted phenyl; and R5 is hydrogen or methyl, useful as active ingredients in pharmaceutical preparation and methods for the treatment of infectious diseases.
