50993-52-7 Usage
Description
[5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium is a chemical compound belonging to the class of diazeniumdiolates, characterized by a diazenium group attached to a 4H-imidazole ring with an ethoxycarbonyl group. [5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium is known for its potential therapeutic applications in the pharmaceutical industry, particularly due to its ability to release nitric oxide (NO), which can have various physiological effects in the human body.
Uses
Used in Pharmaceutical Applications:
[5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium is used as a potential therapeutic agent for various medical conditions, including hypertension, cancer, and neurodegenerative diseases. [5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium's ability to release nitric oxide (NO) makes it a promising candidate for nitric oxide-based therapies, which can help in managing and treating these conditions.
Used in Nitric Oxide-based Therapies:
In the field of nitric oxide-based therapies, [5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium is used as a NO-releasing agent to provide potential treatment options for a range of medical conditions. [5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium's NO-releasing property can help in regulating blood pressure, fighting cancer cells, and alleviating the symptoms of neurodegenerative diseases.
Used in Research and Development:
[5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium is also used in the research and development of new and improved treatments for various medical conditions. Further investigation into the compound's properties and mechanisms of action can lead to the discovery of novel therapeutic approaches and the development of more effective drugs for treating hypertension, cancer, and neurodegenerative diseases.
Used in Drug Delivery Systems:
Similar to gallotannin, [5-(ethoxycarbonyl)-4H-imidazol-4-ylidene]diazenium could potentially be incorporated into drug delivery systems to enhance its applications and efficacy against specific medical conditions. The development of novel drug delivery systems, such as organic and metallic nanoparticles, could improve the compound's delivery, bioavailability, and therapeutic outcomes in treating various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 50993-52-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,9,9 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50993-52:
(7*5)+(6*0)+(5*9)+(4*9)+(3*3)+(2*5)+(1*2)=137
137 % 10 = 7
So 50993-52-7 is a valid CAS Registry Number.
50993-52-7Relevant articles and documents
Synthesis of new azolo[5,1-d][1,2,3,5]tetrazin-4-ones–analogs of antitumor agent temozolomide
Sadchikova
, p. 1867 - 1872 (2017/03/22)
Reactivity of 5-diazoimidazoles and 5-diazopyrazoles in the reactions with alkyland aryl isocyanates was studied. A number of new imidazo-and pyrazolo[5,1-d][1,2,3,5]tetrazin-4 ones were synthesized, which are analogs of temozolomide. It was shown that diazoazoles do not react with isothiocyanates under similar conditions.
Carbene reactivity of 4-diazo-4H-imidazoles toward nucleophiles and aromatic compounds
Smith, Matthew R.,Blake, Alexander J.,Hayes, Christopher J.,Stevens, Malcolm F. G.,Moody, Christopher J.
experimental part, p. 9372 - 9380 (2010/03/04)
(Chemical Equation Presented) Carbenes derived from diazoimidazolecarboxylates 4 under thermal or photochemical conditions undergo O-H and N-H insertion reactions with alcohols and amines, respectively, in moderate yield, in competition with reduction in good H-donor solvents. Dichloromethane reacts to give the corresponding 4-chloroimidazole. Aromatic hydrocarbons are excellent traps for the imidazolylidene carbene and lead to a range of arylimidazole derivatives 7. Reaction with pyridine leads to the first example of a pyridinium ylide 8 formed from an imidazolylidene carbene, whereas irradiation in hexafluorobenzene gives the imidazoazocine 11, presumably by way of an initial norcaradiene intermediate.
Tetrazines
-
, (2008/06/13)
Tetrazines of the formula: wherein R1 represents cycloalkyl, optionally substituted alkyl, alkenyl or alkynyl, A1 represents nitrogen or -CR3= wherein R3 represents hydrogen or a substituent, A2 represents nitrogen or, when A1 represents nitrogen, A2 repr
