5162-03-8 Usage
Description
(2-Chlorophenyl)phenyl-methanone, also known as 2-chlorobenzophenone, is an organic compound that is a metabolite of Clofedanol (C586920). It is characterized by its white to yellow crystalline powder appearance. (2-Chlorophenyl)phenyl-methanone has been investigated for its thermodynamics of formation in the inclusion complex with cyclomaltoheptaose (β-cyclodextrin) using UV-vis spectroscopy and reversed-phase liquid chromatography. Additionally, it undergoes reduction in the presence of LiAlH4 and (R)-(-)-2-(2-iso-indolinyl)butan-1-ol to produce the corresponding benzhydrols.
Uses
Used in Photocrosslinking Applications:
(2-Chlorophenyl)phenyl-methanone is used as a catalyst in the photocrosslinking of polyethylenes, which is an important process in the manufacturing of various plastic products.
Used in Pharmaceutical Synthesis:
(2-Chlorophenyl)phenyl-methanone is utilized in the synthesis of 1-(2-chlorophenyl)isoquinolin-3-yl trifluoromethanesulfonate, which is a compound with potential pharmaceutical applications.
Used in Chemical Research:
(2-Chlorophenyl)phenyl-methanone is also used in chemical research, particularly in the study of its thermodynamics of formation in inclusion complexes, which can provide insights into its potential applications in various chemical and material science fields.
Used in Reduction Reactions:
(2-Chlorophenyl)phenyl-methanone is employed in reduction reactions to afford the corresponding benzhydrols, which can be further used in the synthesis of other organic compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5162-03-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,6 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5162-03:
(6*5)+(5*1)+(4*6)+(3*2)+(2*0)+(1*3)=68
68 % 10 = 8
So 5162-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H9ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H
5162-03-8Relevant articles and documents
Bickel,Fabens
, p. 1450 (1949)
Poly(ethylene glycol) dimethyl ether mediated oxidative scission of aromatic olefins to carbonyl compounds by molecular oxygen
Yu, Tao,Guo, Mingqing,Wen, Simiaomiao,Zhao, Rongrong,Wang, Jinlong,Sun, Yanli,Liu, Qixing,Zhou, Haifeng
, p. 13848 - 13852 (2021/04/22)
A simple, and practical oxidative scission of aromatic olefins to carbonyl compounds using O2as the sole oxidant with poly(ethylene glycol) dimethyl ether as a benign solvent has been developed. A wide range of monosubstituted,gem-disubstituted, 1,2-disubstituted, trisubstituted and tetrasubstituted aromatic olefins was successfully converted into the corresponding aldehydes and ketones in excellent yields even with gram-scale reaction. Some control experiments were also conducted to support a possible reaction pathway.
Photo-induced oxidative cleavage of C-C double bonds for the synthesis of biaryl methanoneviaCeCl3catalysis
Xie, Pan,Xue, Cheng,Du, Dongdong,Shi, SanShan
supporting information, p. 6781 - 6785 (2021/08/20)
A Ce-catalyzed strategy is developed to produce biaryl methanonesviaphotooxidative cleavage of C-C double bonds at room temperature. This reaction is performed under air and demonstrates high activity as well as functional group tolerance. A synergistic Ce/ROH catalytic mechanism is also proposed based on the experimental observations. This protocol should be the first successful Ce-catalyzed photooxidation reaction of olefins with air as the oxidant, which would provide inspiration for the development of novel Ce-catalyzed photochemical synthesis processes.