52752-55-3

Basic information

• Product Name: (Z)-1,4-di(phenoxy)but-2-ene
• Synonyms: (Z)-1,4-di(phenoxy)but-2-ene
• CAS NO: 52752-55-3
• Molecular Weight: 240.302
• Mol File: 52752-55-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (Z)-1,4-di(phenoxy)but-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1,4-di(phenoxy)but-2-ene(52752-55-3)
• EPA Substance Registry System: (Z)-1,4-di(phenoxy)but-2-ene(52752-55-3)

Safety Data

• Hazardous Substances Data: 52752-55-3(Hazardous Substances Data)

Upstream product

• 1708-29-8 2,5-dihydrofuran 
• 108-95-2 phenol 
• 100-46-9 benzylamine 
• 766-94-9 vinyl phenyl ether 
• 2120-70-9 2-phenoxyethanal 
• 192652-08-7 C₂₂H₂₂O₃ 
• 122-99-6 2-Phenoxyethanol 
• 100-67-4 potassium phenolate 
• 109-73-9 N-butylamine 
• 75-61-6 dibromodifluoromethane 
• 75-64-9 tert-butylamine 
• 56-23-5 tetrachloromethane 
• 75-31-0 isopropylamine 
• 72900-28-8 2-((Z)-4-(tetrahydro-2H-pyran-2-yloxy)but-2-enyloxy)-tetrahydro-2H-pyran 

Downstream Products

• 1126-79-0 n-butyl phenyl ether 
• 52752-61-1 (E)-1-phenoxy-1,3-butadiene 
• 71224-53-8 (E,Z)-1,3-butadienyl phenyl ether 

Relevant articles and documents

Reductive C-O, C-N, and C-S Cleavage by a Zirconium Catalyzed Hydrometalation/β-Elimination Approach

A zirconium catalyzed reductive cleavage of Csp3 and Csp2 carbon-heteroatom bonds is reported that makes use of a tethered alkene functionality as a traceless directing group. The reaction is successfully demonstrated on C-O, C-N, and C-S bonds and proposed to proceed via a hydrozirconation/β-heteroatom elimination sequence of an in situ formed zirconium hydride catalyst. The positional isomerization of the catalyst further enables the cleavage of homoallylic ethers and the removal of terminal allyl and propargyl groups.

A new route to amino-2-propanol structures with adrenergic β-blocker activity using low valent titanium

Amino-2-propanol structures can be obtained by addition to dibenzyl acetals of in situ generated dihalocarbenes using LTV (Low Valent Titanium). This methodology can be used to obtain adrenergic β-blockers with amino-2-propanol structure. Tetrahalomethane are the best dihalocarbene precursors. The yields obtained using halofluromethanes can be increased by addition of carbontetrachloride. A process that can imply halogen transfer may be proposed.