5281-22-1

Basic information

• Product Name: Benzene, 1-(2,2-dichloroethenyl)-4-nitro-
• CAS NO: 5281-22-1
• Molecular Formula: C8H5Cl2NO2
• Molecular Weight: 218.039
• Mol File: 5281-22-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2,2-dichloroethenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2-dichloroethenyl)-4-nitro-(5281-22-1)
• EPA Substance Registry System: Benzene, 1-(2,2-dichloroethenyl)-4-nitro-(5281-22-1)

Safety Data

• Hazardous Substances Data: 5281-22-1(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 555-16-8 4-nitrobenzaldehdye 
• 2201-11-8 1,1,1-trichloro-2-(4-nitrophenyl)-ethane 
• 56-23-5 tetrachloromethane 
• 175921-95-6 (E)-1-(4-nitrobenzylidene)hydrazine 
• 6310-10-7 4-nitrobenzaldehyde hydrazone 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 1620143-51-2 ethyl [2,2,2-trichloro-1-(4-nitrophenyl)ethyl]carbonate 
• 54075-25-1 4-nitro-α-(trichloromethyl)benzyl alcohol 
• 75-62-7 Bromotrichloromethane 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 20264-91-9 1-(chloroethynyl)-4-nitrobenzene 
• 1353724-94-3 ethyl 1-chloro-2-(4-nitrophenyl)indolizine-3-carboxylate 
• 1353724-96-5 1-chloro-2-(4-nitrophenyl)indolizine-3-carbonitrile 
• 15852-01-4 1-chloro-4-[(4-nitrophenyl)ethynyl]benzene 
• 64583-21-7 1-fluoro-4-(2-(4-nitrophenyl)ethynyl)benzene 
• 1942-30-9 4-(phenylethynyl)nitrobenzene 
• 126521-89-9 1,3-benzothiazol-2-yl(4-nitrophenyl)methanone 
• 1367843-31-9 4-chloro-3-(4-nitrophenyl)-1-phenyl-1H-pyrazole 
• 1370287-78-7 4-chloro-1-(4-methoxyphenyl)-3-(4-nitrophenyl)-5-phenyl-1H-pyrazole 
• 1370287-77-6 4-chloro-3-(4-nitrophenyl)-1,5-diphenyl-1H-pyrazole 
• 1367843-35-3 4-chloro-3-(4-nitrophenyl)-1-p-tolyl-1H-pyrazole 
• 1367843-41-1 4-chloro-1-(4-methoxyphenyl)-3-(4-nitrophenyl)-1H-pyrazole 

Relevant articles and documents

Visible-Light-Mediated Z -Stereoselective Monoalkylation of β,β-Dichlorostyrenes by Photoredox/Nickel Dual Catalysis

Metal-catalyzed alkylation of 1,1-dihalovinyl moiety commonly suffers from both a lack of stereoselectivity and the overreaction leading to the dialkylation product. The methodology described herein features a new pathway to alkylate stereoselectively β,β-dichlorostyryl substrates to provide the Z -trisubstituted olefin only with fair to good yields. This cross-coupling reaction bears on the smooth and photoinduced formation of a C-centered radical that engages in a nickel-catalyzed organometallic cycle to form the key C sp2-C sp3bond.

Ionic liquids as a reusable media for copper catalysis. Green access to alkenes using catalytic olefination reaction

It was demonstrated that ionic liquids are superb recyclable media for copper catalyzed reactions using catalytic olefination reaction as an example. As a result a novel green access to the halogenoalkenes was elaborated. Possibility to perform up to five reaction cycles without catalyst leaching and decreasing of the yield was demonstrated. A number of various ionic liquids was screened and 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim] [BF4]) was found the solvent with highest efficiency. Mild conditions, high atom economy comparing to other known methods, low amounts of wastes and possibility to recover ionic liquid are the advantages of the proposed method.

Convenient synthesis of 2-aryl-1-haloindolizines from pyridinium salts and 2-aryl-1,1-dihaloalk-1-enes

2-Aryl-1-haloindolizines were synthesized from pyridinium salts and 2-aryl-1,1-dihaloalk-1-enes using a DBU/THF system. 2-Aryl-1,1-dihaloalk-1-enes containing electron-withdrawing or -donating groups were efficiently converted into the corresponding 2-aryl-1-haloindolizines in moderate to excellent yields. Georg Thieme Verlag Stuttgart.