5409-59-6 Usage
Description
(3E)-1,4-diphenylbut-3-en-2-one, commonly known as chalcone, is a benzylideneacetophenone chemical compound characterized by its yellow solid appearance. With a molecular formula of C15H12O and a molecular weight of 208.25 g/mol, chalcone is recognized for its intriguing chemical properties and promising biological activities, including antioxidant, anti-inflammatory, and anticancer properties. These characteristics position chalcone as a potential therapeutic agent for a range of diseases and a versatile compound in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
Chalcone is utilized as an active pharmaceutical ingredient due to its demonstrated antioxidant, anti-inflammatory, and anticancer activities. Its potential therapeutic value makes it a candidate for the treatment of various diseases, particularly those related to oxidative stress and inflammation.
Used in Organic Synthesis:
In the field of organic synthesis, chalcone serves as a key intermediate and a valuable building block for the creation of more complex molecules. Its unique structure allows for further functionalization and modification, contributing to the development of novel compounds with specific applications.
Used as a Fluorescent Dye:
Chalcone's potential as a fluorescent dye has been explored, capitalizing on its ability to emit light upon excitation. This characteristic can be harnessed in various analytical and diagnostic applications where the detection and visualization of specific molecules or biological processes are required.
Used as a Precursor for Pharmaceutical Compounds:
Chalcone is recognized as a precursor in the synthesis of a variety of pharmaceutical compounds. Its versatility in chemical reactions enables the production of diverse molecules with different therapeutic properties, expanding the scope of available treatments for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5409-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,0 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5409-59:
(6*5)+(5*4)+(4*0)+(3*9)+(2*5)+(1*9)=96
96 % 10 = 6
So 5409-59-6 is a valid CAS Registry Number.
5409-59-6Relevant articles and documents
2:1 versus 1:1 Coupling of Alkylacetylenes with Secondary Amines: Selectivity Switching in 8-Quinolinolato Rhodium Catalysis
Morimoto, Yoshihiko,Hamada, Moe,Takano, Shotaro,Mochizuki, Katsufumi,Kochi, Takuya,Kakiuchi, Fumitoshi
supporting information, p. 3803 - 3808 (2021/04/05)
Both 2:1 and 1:1 couplings of alkylacetylenes with secondary amines were achieved using 8-quinolinolato rhodium catalysts and CsF. The 2:1/1:1 selectivity was switched by choosing the reaction solvent. In DMA, an unprecedented 2:1 coupling reaction of alkylacetylenes with amines proceeded to give 2-aminodiene products. One-pot 2:1 coupling/reduction provided rapid access to various allylamines, while one-pot coupling/hydrolysis gave enones as products. In toluene, anti-Markovnikov hydroamination occurred under relatively mild conditions to give 1:1 coupling products.
Synthesis of (E)-stilbenes and (E,E)-1,4-diphenylbuta-1,3-diene promoted by boron trifluoride-diethyl ether complex
Narender,Papi Reddy,Madhur
scheme or table, p. 3791 - 3796 (2010/03/04)
An efficient, simple, and practical method has been de-veloped to regioselectively synthesize (E)-stilbenes and (E,E)-1,4diphenylbuta-1,3-diene in good to excellent yields in the presence of boron trifluoride-diethyl ether complex as a catalyst in a short reaction (30-60 s) at room temperature. Georg Thieme Verlag Stuttgart.
Enamine synthesis using the Horner-Wittig reaction. Part 2. New acyl anion equivalents derived from (aminomethyl)diphenylphosphine oxides
Broekhof, N. L. J. M.,Elburg, P. van,Hoff, D. J.,Gen, A. van der
, p. 317 - 321 (2007/10/02)
Using the Horner-Wittig reagents (1-morpholino-alkyl)diphenylphosphine oxides (1), aromatic as well as aliphatic α,β-unsaturated aldehydes can be converted into the morpholino enamines of their respective homologous phenyl, ethyl and styryl ketones.These enamines can be easily converted into the corresponding ketones by mild, acid-catalyzed hydrolysis.The usefulness of these phosphine oxides as acyl anion equivalents is further demonstrated by the synthesis of dihydrojasmone and of (Z)-6-henicosen-11-one.
