54280-91-0Relevant articles and documents
Metal chloride-promoted aldol reaction of α-dimethylsilylesters with aldehydes, ketones, and α-enones
Miura, Katsukiyo,Nakagawa, Takahiro,Hosomi, Akira
, p. 1917 - 1921 (2005)
In the presence of a catalytic amount of LiCl, α-dimethylsilylesters (α-DMS-esters) 1 smoothly reacted with various aldehydes at 30°C to give aldols in good to high yields. On the other hand, the aldol reaction with ketones was effectively promoted by MgCl2 rather than by LiCl. α-Enones also underwent the metal chloride-promoted addition of 1 at the carbonyl carbon or β-carbon. Georg Thieme Verlag Stuttgart.
Lithium Benzenetellurolate-induced Reformatsky-type Reaction in the Presence of Cerium Trichloride
Fukuzawa, Shin-ichi,Hirai, Katsuhiko
, p. 1963 - 1966 (2007/10/02)
Reformatsky-type reactions with PhTeLi in the presence of CeCl3 proceeded smoothly under mild conditions.The PhTeLi-CeCl3 reagent was particularly efficient for the reactions of sterically hindered and enolizable ketones; in the absence of CeCl3 unsatisfactory yields of the desired β-hydroxy ketone were obtained.It is assumed that CeCl3 reactions involve a cerium enolate intermediate.The stereoselectivity of the reaction between ethyl 2-bromopropionate and benzaldehyde is also described.