5433-10-3

Basic information

• Product Name: 3-{[(E)-(4-methoxyphenyl)methylidene]amino}propan-1-ol
• CAS NO: 5433-10-3
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• Mol File: 5433-10-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 333°C at 760 mmHg
• Flash Point: 155.2°C
• Density: 1.02g/cm³
• Vapor Pressure: 5.58E-05mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 3-{[(E)-(4-methoxyphenyl)methylidene]amino}propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{[(E)-(4-methoxyphenyl)methylidene]amino}propan-1-ol(5433-10-3)
• EPA Substance Registry System: 3-{[(E)-(4-methoxyphenyl)methylidene]amino}propan-1-ol(5433-10-3)

Safety Data

• Hazardous Substances Data: 5433-10-3(Hazardous Substances Data)

Usage

General Description

3-{[(E)-(4-methoxyphenyl)methylidene]amino}propan-1-ol is a chemical compound with the molecular formula C11H15NO2. It is a derivative of propan-1-ol and contains a substituted amino group and a methoxyphenyl group. The compound is likely to have applications in various fields such as pharmaceuticals, organic synthesis, and research. It may also exhibit different chemical and physical properties based on its molecular structure, making it a potential candidate for further study and development.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 156-87-6 propan-1-ol-3-amine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 91340-37-3 3-{[(4-methoxyphenyl)methyl]amino}propan-1-ol 

Relevant articles and documents

Olefin Amine (OLA) Reagents for the Synthesis of Bridged Bicyclic and Spirocyclic Saturated N-Heterocycles by Catalytic Hydrogen Atom Transfer (HAT) Reactions

Spiro- and bridged bicyclic structures are in demand for their sp3-rich frameworks that offer unique physiochemical properties and precisely positioned substituent groups. In order to rapidly access such molecules in a cross-coupling fashion we describe olefin amine (OLA) reagents for the transformation of aldehydes and ketones into all three topological types of bicyclic N-heterocycles: bridged, spiro-, and fused rings. The OLA reagents are easily prepared and allow the synthesis of complex molecular frameworks under operationally simple conditions that tolerate a wide array of functional groups. Investigations into the Mn or Fe promoted reaction pathway support a metal hydride hydrogen atom transfer (MH-HAT) to generate a C-centered radical that undergoes addition to an unactivated imine, leading to an N-centered radical. A catalytic cycle featuring regeneration of the metal catalyst by O2 and a second HAT to form the unprotected saturated N-heterocycle appears to be operative.

Nano-tube TiO2 as a new catalyst for eco-friendly synthesis of imines in sunlight

Nanomaterials are considered as suitable heterogeneous catalysts for many organic reactions. Herein nano-tube TiO2 has been reported as a heterogeneous catalyst, for synthesis of imines in sunlight at room temperature under solvent-free conditions. The condensation of less electrophilic carbonyl compounds with poorly nucleophilic amines was afforded imines in excellent yields.

SIMPLE SYNTHESIS OF 3-(N-ALKYLAMINO)-1-PROPANOLS

Various 3-(N-alkylamino)-1-propanols were obtained by the lithium aluminum hydride reduction of the products of the reaction of 3-amino-1-propanol with carbonyl compounds.This method for the synthesis of aminopropanols is applicable in the case of optimal electrophilicity of the carbonyl component.