5437-50-3Relevant articles and documents
Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides
Pradère, Ugo,Roy, Vincent,Montagu, Aurélien,Sari, Ozkan,Hamada, Manabu,Balzarini, Jan,Snoeck, Robert,Andrei, Graciela,Agrofoglio, Luigi A.
, p. 126 - 133 (2013/01/15)
Seventeen hitherto unknown bis(POM) prodrugs of novel (E)-[4′- phosphono-but-2′-en-1′-yl]purine nucleosides were prepared in a straight approach and at good yields. Those compounds were synthesized by the reaction of purine nucleobases directly with the p
Solution-phase synthesis of 2,6,9-trisubstituted purines
Fiorini, Maria T.,Abell, Chris
, p. 1827 - 1830 (2007/10/03)
A simple three-step method for the solution-phase combinatorial synthesis of 2,6,9-trisubstituted purines from 2,6-dichloropurine is described. The synthesis exploits the use of resin capture to remove excess reagent used in the final step.