55212-79-8

Basic information

• Product Name: 2-Butenoic acid, 3-(1-pyrrolidinyl)-, methyl ester, (2E)-
• CAS NO: 55212-79-8
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.224
• Mol File: 55212-79-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 3-(1-pyrrolidinyl)-, methyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 3-(1-pyrrolidinyl)-, methyl ester, (2E)-(55212-79-8)
• EPA Substance Registry System: 2-Butenoic acid, 3-(1-pyrrolidinyl)-, methyl ester, (2E)-(55212-79-8)

Safety Data

• Hazardous Substances Data: 55212-79-8(Hazardous Substances Data)

Upstream product

• 5469-24-9 methyl 2,3-dibromobutyrate 
• 92234-51-0 methyl β-(1-imidazolyl)crotonoate 
• 123-75-1 pyrrolidine 
• 105-45-3 acetoacetic acid methyl ester 
• 91164-90-8 3-((Z)-2-Methoxycarbonyl-1-methyl-vinyl)-1-methyl-3H-imidazol-1-ium; iodide 

Downstream Products

• 87565-77-3 methyl 2-methyl-4-pyrrolidino-6-hydroxybenzoate 
• 33598-27-5 (+/-)-3-(1-pyrrolidinyl)butyric acid methyl ester 
• 105-25-9 1-(2-buten-1-yl)pyrrolidine 
• 116431-49-3 3-Oxo-2-((2R,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-butyric acid methyl ester 
• 1357268-73-5 methyl 4,4-difluoro-3-methyl-4-(phenylsulfonyl)-3-(pyrrolidin)-1-ylbutanoate 
• 83577-52-0 methyl 7-phenyl-3-pyrrolidinohepta-2E,4E,6E-trienoate 
• 83577-50-8 methyl 5-phenyl-3-pyrrolidinopenta-2E,4E-dienoate 
• 83577-57-5 4-pyrrolidino-6-phenyl-1,2-pyrone 
• 117648-47-2 5-Benzyl-2,5-dihydro-4-pyrrolidino-2-thiophen 
• 24838-35-5 1,1'-biphenyl-3,5-diyl-bis-pyrrolidine 
• 74105-96-7 2-Hydroxy-4-methyl-6-pyrrolidinobenzoesaeure-methylester 
• 96722-36-0 2,4-Dimethyl-6-pyrrolidinobenzoeseure-methylester 
• 30736-25-5 (3E)-5-((Ξ)-5-oxo-2-phenyl-oxazol-4-ylidene)-3-pyrrolidin-1-yl-pent-3-enoic acid methyl ester 

Relevant articles and documents

Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus

A compound represented by a genera formula (Ia) or (Ib) and a stereo-selective preparation method thereof using a carbonyl reductase which is separated from Kluyveromyces marxianus. The compound can be prepared by reduction of substituted β-keto ester and can be used as an intermediate in preparing β-lactam group antibiotics.

Self-condensation of (β-Alkoxycarbonylalkylidene)ammonium Salts

Iminium chlorides or trifluoroacetates of type 2, formed by protonation of β-(alkoxycarbonyl)-enamines 1, have been proved to undergo condensation to give derivatives of 4-alkyl-2-amino-6-hydroxybenzoic acid 6 via elimination of ammonium salt and alcohol.The structures of 6 had been established by spectroscopic data as well as by further reactions.The range of application of this condensation reaction has been studied and the mechanism is discussed.In the primary step presumably a nucleophilic attack on the alkoxycarbonyl group of the iminium salt 2 takes place by the enamine 1 present in the equilibrium.Analogous reactions are also found for homologues of the enamine 1 (e.g. 11, 13 and 17) to give the condensation products 12, 14, 15, and 20.