5543-98-6 Usage
Description
2-(4-Hydroxyphenyl)-1,2-diphenyl-ethanone, also known as Benzophenone-4, is an organic compound with the molecular formula C15H12O2. It is a white crystalline solid that is soluble in organic solvents and has a melting point of 92-94°C. Benzophenone-4 is characterized by its aromatic ketone structure, which consists of a carbonyl group (C=O) bonded to two phenyl rings. 2-(4-Hydroxyphenyl)-1,2-diphenyl-ethanone is known for its photochemical properties and is widely used in various applications.
Uses
Used in Photoinitiator Applications:
2-(4-Hydroxyphenyl)-1,2-diphenyl-ethanone is used as a photoinitiator in the curing of hexanediol diacrylate. It is an effective initiator for the polymerization process, promoting the formation of cross-linked networks in the material. This application is particularly useful in the production of coatings, adhesives, and other polymer-based materials, where rapid curing and high performance are required.
Used in Pharmaceutical Industry:
2-(4-Hydroxyphenyl)-1,2-diphenyl-ethanone serves as an intermediate in the preparation of clomiphene and tamoxifen analogs. Clomiphene and tamoxifen are selective estrogen receptor modulators (SERMs) that are used in the treatment of various medical conditions, including infertility and breast cancer. Benzophenone-4 plays a crucial role in the synthesis of these pharmaceutical compounds, contributing to their development and therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 5543-98-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,4 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5543-98:
(6*5)+(5*5)+(4*4)+(3*3)+(2*9)+(1*8)=106
106 % 10 = 6
So 5543-98-6 is a valid CAS Registry Number.
5543-98-6Relevant articles and documents
PROCESS FOR CREATING CARBON-CARBON BONDS USING CARBONYL COMPOUNDS
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Paragraph 0434-0440, (2015/06/24)
The present invention concerns a process for preparing a compound of formula (I) by reaction between a compound of formula (II) and a compound of formula (III) in the presence of a copper-containing catalyst, a ligand and base. The invention also concerns the implementing of this process for the preparation of building blocks to prepare molecules of interest in particular in the pharmaceutical, agro-chemical fields, etc.
Reaction of pyrylium salts with nucleophiles. 23: Triarylethene derivatives containing an oxyalkyleneamino or oxyalkylene-N-pyridinium side chain
Stanciuc,Balaban
, p. 927 - 933 (2007/10/02)
A synthetic design was devised for preparing primary amines related to anticancer drugs clomiphene and tamoxifen on the basis of key intermediates with a phenolic group, to which a side chain (ω-aminoethoxy or ω- aminopropoxy) was attached. These compound