56674-68-1

Basic information

• Product Name: 2-(cyclohexyloxy)propanoic acid
• Synonyms: 2-(cyclohexyloxy)propanoic acid
• CAS NO: 56674-68-1
• Molecular Weight: 172.224
• Mol File: 56674-68-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(cyclohexyloxy)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cyclohexyloxy)propanoic acid(56674-68-1)
• EPA Substance Registry System: 2-(cyclohexyloxy)propanoic acid(56674-68-1)

Safety Data

• Hazardous Substances Data: 56674-68-1(Hazardous Substances Data)

Usage

General Description

2-(cyclohexyloxy)propanoic acid is a chemical compound with the molecular formula C9H16O3. It is a carboxylic acid with a cyclohexyloxy group attached to the second carbon of a propanoic acid molecule. 2-(cyclohexyloxy)propanoic acid is commonly used in the synthesis of pharmaceuticals and organic compounds. It has potential applications in the development of drugs for various medical conditions. The chemical properties of 2-(cyclohexyloxy)propanoic acid make it a valuable building block in the field of organic chemistry, with the potential to be used as a precursor in the creation of new compounds for medical and industrial purposes.

Upstream product

• 27131-71-1 2-methyl-3-oxo-1,4-dioxaspiro<4.5>decane 
• 60-29-7 diethyl ether 
• 677-22-5 tert-butylmagnesium chloride 
• 598-78-7 (R,S)-2-chloropropionic acid 
• 108-93-0 cyclohexanol 
• 940-31-8 2-phenoxypropionic acid 
• 22096-22-6 sodium cyclohexanolate 

Downstream Products

• 86867-77-8 2,4,6-Trimethyl-benzenesulfonic acid 3-cyclohexyloxy-2-oxo-butyl ester 
• 86867-76-7 Toluene-4-sulfonic acid 3-cyclohexyloxy-2-oxo-butyl ester 
• 86867-73-4 Benzenesulfonic acid 3-cyclohexyloxy-2-oxo-butyl ester 
• 86867-79-0 3-cyclohexyloxy-1-diazo-2-butanone 

Relevant articles and documents

Further structure-activity relationships in the series of tropanyl esters endowed with potent antinociceptive activity

Several analogs of the α-tropanyl esters of 2-(4-chlorophenoxy)butyric acid (SM21) and 2-phenylthiobutyric acid (SM32), endowed with potent antinociceptive and cognition enhancing activity, were synthesized, aimed at obtaining more potent and safe drug candidates. Variation of the acyl moiety, as well as the conformational restriction of atropine to give the α-tropanyl ester of 2,3-dihydrobenzofurane-3-carboxylic acid (18), practically abolished activity. In the case of 18, the antimuscarinic activity was also severely affected by the conformation restrain. On the contrary, conformational restriction of phenoxybutyric and phenylthiobutyric acid derivatives to give the α-tropanyl ester of 2,3-dihydro-benzofurane-2-carboxylic acid and 2,3-dihydro-benzothiophene-2-carboxylic acid, afforded potent analgesic drugs that unfortunately were too toxic to be reliable drug candidates. A series of related esters of benzofurane-3-carboxylic acid and benzothiophene-3-carboxylic acid were also studied and found to be potent but toxic analgesics.